key: cord-0891738-phvknyc7 authors: Dai, Huiyang; Zhang, Stephen X.; Looi, Kim Hoe; Su, Rui; Li, Jizhen title: Perception of Health Conditions and Test Availability as Predictors of Adults’ Mental Health during the COVID-19 Pandemic: A Survey Study of Adults in Malaysia date: 2020-07-30 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17155498 sha: 85cd95aec8673046ed8cf51c3520e5ee6b3413a3 doc_id: 891738 cord_uid: phvknyc7 Research identifying adults’ mental health during the coronavirus disease 2019 (COVID-19) pandemic relies solely on demographic predictors without examining adults’ health condition as a potential predictor. This study aims to examine individuals’ perception of health conditions and test availability as potential predictors of mental health—insomnia, anxiety, depression, and distress—during the COVID-19 pandemic. An online survey of 669 adults in Malaysia was conducted during 2–8 May 2020, six weeks after the Movement Control Order (MCO) was issued. We found adults’ perception of health conditions had curvilinear relationships (horizontally reversed J-shaped) with insomnia, anxiety, depression, and distress. Perceived test availability for COVID-19 also had curvilinear relationships (horizontally reversed J-shaped) with anxiety and depression. Younger adults reported worse mental health, but people from various religions and ethnic groups did not differ significantly in reported mental health. The results indicated that adults with worse health conditions had more mental health problems, and the worse degree deepened for unhealthy people. Perceived test availability negatively predicted anxiety and depression, especially for adults perceiving COVID-19 test unavailability. The significant predictions of perceived health condition and perceived COVID-19 test availability suggest a new direction for the literature to identify the psychiatric risk factors directly from health-related variables during a pandemic. In May 2020, the United Nations Secretary-General issued a message that the coronavirus disease 2019 (COVID-19) pandemic had resulted in massive mental suffering and called for actions [1] . Research is critically needed on mental health of patients, healthcare workers, and the general population during the COVID-19 pandemic. Distress, anxiety, depression, and insomnia are relevant mental health disorders due to their prevalence during severe acute respiratory syndrome (SARS) and COVID-19 outbreaks [2] [3] [4] [5] . A number of studies have predicted mental health by means of demographic variables [2, 3, 6] , but little research has predicted mental health during the COVID-19 pandemic based on adults' health-related variables. This study aims to examine individuals' perception of health The data for this study were collected by an online survey from May 2 to 8, 2020, six weeks after the implementation of the MCO in Malaysia. On 8 May 2020, there were a total of 6535 confirmed cases of COVID-19 and 108 deaths [14] . We applied a two-stage stratified sampling. In the first stage, we did stratified sampling based on regions, specifically the principal administrative divisions in Malaysia of 13 states (Negeri) and 3 federal territories (Wilayah Persekutuan). In the second stage, we did cluster-sampling based on the ethnicity, gender, and age groups [15] of the Malaysian population [16] . To minimize response and measurement bias, we followed the standard survey approaches [17] , i.e., no social pressure to influence responses, no questions that provoke defensiveness or threaten esteem, no payoff or cost for particular responses. Multi-item questions were used to ensure no priming, and there was no overlapping among questions for different constructs [18] . Participation in this survey was voluntary, and participants could opt out at any time. Moreover, participants were assured anonymity and confidentiality of their responses. The survey was granted ethical approval by Tsinghua University (20200322). The online survey was issued in Malay, Mandarin, and English, the three major languages used in Malaysia. Given that the survey was entirely voluntary, and the introduction provided the estimated minutes to complete the survey as well as consent form, 89.7% of the adults (669 out 746) who consented to participate finished the survey. All of the 669 participants were found to be above 18 years old and, hence, fulfilled the eligibility of the criterion of adulthood in Malaysia to be included in this study. The participants reported their demographic characteristics, including gender, age, education level, number of children under 18 years old in the household, religion, and ethnic group. We assessed health condition using the global health measure SF-1 [19] with a five-point scale from 1 to 5 (poor, fair, good, very good, excellent). To capture perceived availability of testing for COVID-19 in Malaysia, we asked participants to rate the statement "I can get a test for COVID-19 rapidly if I need it" from 1 to 7 (strongly disagree, disagree, somewhat disagree, neither agree nor disagree, somewhat agree, agree, strongly agree). We used four dimensions for mental health: insomnia, anxiety, depression, and distress. They were all measured with commonly used established scales in literature. To examine the reliability of each construct, Cronbach's alpha was computed [20] . Adults' insomnia was measured with the five-item Athens Insomnia Scale (AIS-5) [21] , including "I have trouble falling asleep" and "I feel tired and worn-out after my usual amount of sleep". The items were scored from 1 (to a very small extent) to 5 (to a very large extent). The Cronbach's alpha was 0.82. The average score constructed with Cronbach's alpha was used to evaluate insomnia. Adults' anxiety was measured by the seven-item generalized anxiety disorder (GAD-7) [22] scale. The seven items were scored from 0 (not at all) to 3 (nearly every day). The Cronbach's alpha was 0.92. The total score of seven items was used to evaluate anxiety. Adults' depression was measured with the nine-item Patient Health Questionnaire depression module (PHQ-9) [23] , with items scored from 0 (not at all) to 3 (nearly every day). The Cronbach's alpha was 0.90. The total score of nine items was used to evaluate depression. Adults' psychological distress was measured with the six-item K6 screening scale [24] , with items scored from 1 (all of the time) to 5 (none of the time). The Cronbach's alpha was 0.95. The total score of six items was used to evaluate depression. We analyzed the data using STATA software version 16.0 (StataCorp LLC, College Station, Texas, USA). We used multivariable least-squares regression analysis to predict the risk factors for the mental health disorders of Malaysian adults at a significance level of 0.05. The associations between risk factors and outcomes were adjusted for confounders, following other psychiatric studies under COVID-19 [25] . Overall, 669 adults from all the states and federal territories of Malaysia participated in this survey. (Data will be available on request for the readers.) Table 1 shows the descriptive statistics of the sample. Participation by both genders was almost equal. The youngest participant was 21 years old and the oldest was 71 years old. Malaysia is a diverse country in terms of ethnicity and religion. Religion and ethnicity are reported in Table 1 . Overall, our sample captured all the major ethnic and religious groups in Malaysia, but the sample is not taken as representative. According to Table 1 , the mean scores of insomnia (AIS-5), anxiety (GAD-7), depression (PHQ-9), and distress (K6) were 1.76 (standard deviation (SD) = 0.84), 4.36 (SD = 4.89), 4.49 (SD = 5.03), and 5.10 (SD = 5.73), respectively. Table 2 presents the results of the regression models. The quadratic terms of health condition (health condition-square in Table 2 ) were significantly positive across the regressions for all four dimensions of mental health: insomnia, anxiety, depression, and distress. This demonstrates curvilinear relationships between health condition and mental health dimensions. The margin analysis of the slope of insomnia by health condition was −0.71 (p < 0.001) at "poor", −0.51 (p < 0.001) at "fair", −0.31 (p < 0.001) at "good", −0.10 (p = 0.017) at "very good", and 0.10 (p = 0.328) at "excellent" health condition, showing a horizontally reversed J-shaped curve across the scoring range of health condition. Similar curvilinear relationships were also observed for anxiety, depression, and distress. The slope of anxiety was −5.34 (p < 0.001) at "poor", −3.76 (p < 0.001) at "fair", −2.18 (p < 0.001) at "good", −0.60 (p = 0.019) at "very good", and 0.98 (p = 0.114) at "excellent" health condition. The slope of depression was −5.04 (p < 0.001) at "poor", −3.55 (p < 0.001) at "fair", −2.06 (p < 0.001) at "good", −0.57 (p = 0.024) at "very good", and 0.91 (p = 0.104) at "excellent" health condition. The slope of distress was −3.11 (p = 0.006) at "poor", −2.21 (p = 0.002) at "fair", −1.32 (p < 0.001) at "good", −0.43 (p = 0.188) at "very good", and 0.46 (p = 0.511) at "excellent" health condition. The quadratic term of test availability (test availability-square in Table 2 ) was positively associated with anxiety and depression. The margin analysis of the slope of anxiety by test availability was −1.49 (p < 0.004) at "strongly disagree", −1.15 (p = 0.002) at "disagree", −0.81 (p < 0.001) at "somewhat disagree", −0.48 (p < 0.001) at "neither disagree nor agree", −0.14 (p = 0.311) at "somewhat agree", 0.19 (p = 0.423) at "agree", and 0.53 (p = 0.152) at "strongly agree", showing a horizontally reversed J-shaped curve across the scoring range of test availability. The slope of depression by test availability demonstrated a similar pattern at the 7-point anchor: −1.41 (p = 0.005) at "strongly disagree", −1.10 (p = 0.003) at "disagree", −0.79 (p < 0.001) at "somewhat disagree", −0.48 (p < 0.001) at "neither disagree nor agree", −0.17 (= 0.263) at "somewhat agree", 0.16 (p = 0. 562) at "agree", and 0.46 (p = 0.227) at "strongly agree". In addition, age negatively predicted insomnia, anxiety, depression, and distress as shown in Table 2 . Insomnia, anxiety, depression, and distress did not vary significantly by religion and ethnicity. The predicted values of insomnia, anxiety, depression, and distress by health conditions, test availability, and age are shown in Figure 1 . This study identified adults' perceived health conditions, perceived test availability, and age as the predictors of their insomnia, anxiety, depression, and distress during the COVID-19 pandemic. The average levels of insomnia, anxiety, depression, and distress of this study in Malaysia are different from adults in other countries under the COVID-19 pandemic ( Table 1 ). The mean scores of depression and anxiety in Malaysia were significantly lower than those in a sample of 300 adults collected on 31 January to 7 February 2020 in China [21] of 8.3 and 7.7, and also lower than scores in a sample of 1009 adults on 10-20 April 2020 in Austria [22] of 6.20 and 5.85. The average level of distress in a sample of 369 working adults (mean = 8.46) in China [23] was significantly higher than in our sample. The proportion of insomnia disorder in our sample (38.9%, n = 669) was approximate to that in a sample collected during 10-13 April 2020 in Greece (37.6%, n = 2427) during the COVID-19 pandemic [24] . Consistent with past studies [6, 26] , age was found to be a predictor of mental health problems for the general population in Malaysia. This is also consistent with studies of healthcare workers, where older healthcare workers were less likely to have mental health problems [27, 28] . However, other predictors found in the literature, such as education [25] and gender [29] , failed to predict mental health among adults in Malaysia, similar to a study in the UK [6] . Our results suggest that This study identified adults' perceived health conditions, perceived test availability, and age as the predictors of their insomnia, anxiety, depression, and distress during the COVID-19 pandemic. The average levels of insomnia, anxiety, depression, and distress of this study in Malaysia are different from adults in other countries under the COVID-19 pandemic ( Table 1 ). The mean scores of depression and anxiety in Malaysia were significantly lower than those in a sample of 300 adults collected on 31 January to 7 February 2020 in China [21] of 8.3 and 7.7, and also lower than scores in a sample of 1009 adults on 10-20 April 2020 in Austria [22] of 6.20 and 5.85. The average level of distress in a sample of 369 working adults (mean = 8.46) in China [23] was significantly higher than in our sample. The proportion of insomnia disorder in our sample (38.9%, n = 669) was approximate to that in a sample collected during 10-13 April 2020 in Greece (37.6%, n = 2427) during the COVID-19 pandemic [24] . Consistent with past studies [6, 26] , age was found to be a predictor of mental health problems for the general population in Malaysia. This is also consistent with studies of healthcare workers, where older healthcare workers were less likely to have mental health problems [27, 28] . However, other predictors found in the literature, such as education [25] and gender [29] , failed to predict mental health among adults in Malaysia, similar to a study in the UK [6] . Our results suggest that future research should identify the effect of education and gender across more countries, and future meta-analysis should identify specific contingent factors. Religion and ethnic groups did not predict Malaysian adults' mental health, consistent with another Malaysian study [30] which found that ethnicity was not correlated with mental health disorders. In line with previous research, our findings highlight the need to identify specific predictors of mental health under various contexts of the COVID-19 pandemic [27] . More importantly, this study uncovers two unique risk factors for mental health. The first risk factor is existing health condition. Previous research found positive associations between physical health condition and mental disorders [7, 10] , yet we found that individuals' health conditions had significant curvilinear relationships with their insomnia, anxiety, depression, and distress. The results indicated that adults with worse health conditions had worse mental health, and this association was more negative for those at the lower end of the health spectrum. Our findings suggest individuals' perceived health conditions can be a useful screener of insomnia, anxiety, depression, and distress during the COVID-19 pandemic. The second risk factor is perceived test availability for COVID-19, which had curvilinear relationships with anxiety and depression. Perceived test unavailability predicted worse anxiety and depression, especially for people who disagreed that they could get tested for COVID-19 when needed. There was also no significant difference in mental health among people who "somewhat agreed", "agreed", and "strongly agreed" that they could get a COVID-19 test. Most people lack data on the actual test availability, and they must rely on their perceptions. We believe perceived test availability could be a predictor of mental health, especially among adults who lack access to COVID-19 tests. Our findings suggest that healthcare service providers could use adults' perceived health conditions and perceived COVID-19 test availability to identify mentally vulnerable adults. The curvilinear relationships highlight the need to pay more attention to adults with perceived poor health conditions and adults who believe they lack access to a COVID-19 test. Healthcare service providers such as hospitals may be able to use the prior health records of their patients and COVID-19 testing coverage to help identify those who need more mental health assistance. The study has several limitations. Firstly, because we aimed to identify predictors for healthcare service providers in developing screening for mental disorders, cross-sectional data were used and should not be taken as evidence of causality. Secondly, we used SF-1, a brief one-item measure of general health condition, and future research may use the lengthier form of SF-12 or SF-36. Thirdly, instead of perceived health conditions, future research may explore specific medical issues, such as heart disease, diabetes, or cancer, as predictors of mental health. Fourthly, we measured adults' perceived test availability for COVID-19 because we were interested in their mental health, and future research may use alternative indicators of COVID-19 test availability. Finally, because we sent out questionnaires online, only adults who have access to the internet in Malaysia could participate in the survey. The internet penetration rate in Malaysia (86% in 2018) [31] might introduce another source of limitation on the generalizability. This study identified two unique predictors of mental health in individuals' perceived health conditions and perceived COVID-19 test availability. Perceived health condition predicted insomnia, anxiety, depression, and distress, and perceived test availability predicted anxiety and depression. Unlike the demographic predictors identified in prior research, this study suggests two new risk factors to predict mental health problems. Moreover, these predictors carried quadratic associations with various mental health dimensions, implying a need to focus on curvilinear predictors of mental health. 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Insomnia during the COVID-19 pandemic in a Greek population An overview of the mental health burden in Malaysia Malaysia's Internet Penetration is Now 85.7 Percent This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license We acknowledge the support of Research Center for Competitive Dynamics and Innovation Strategy, School of Economics and Management, Tsinghua University. We acknowledge assistance from Meghana Kotha. The authors declare no conflict of interest with respect to the research, authorship, and/or publication of this article.