key: cord-0889428-18khnb1k authors: Blanchet, Karl; Mallard, Grégoire; Moret, Erica; Sun, Jin title: Sanctioned countries in the global COVID-19 vaccination campaign: the forgotten 70% date: 2021-09-17 journal: Confl Health DOI: 10.1186/s13031-021-00404-2 sha: 14f9130ff51c4aa49611e96225b8254277b21610 doc_id: 889428 cord_uid: 18khnb1k COVAX, the global initiative on COVID-19 vaccines, has set the target of achieving a COVID-19 vaccination coverage of up to 30% of the population of 135 countries in 2 years. Here, we argue that COVAX should anticipate important and unforeseen challenges with regard to sanctioned countries. For those, COVAX needs to provide a higher percentage of the vaccines. Otherwise, the problems of vaccination will linger, risking the advent of new variants and preventing an effective global response in reigning the pandemic under control. COVAX, the global initiative on COVID-19 vaccines, has set the target of achieving a COVID-19 vaccination coverage of up to 30% [1] of the population of 135 countries in 2 years [2] , with advance commitment to ensure access for 92 low-and middle-income countries (LMICs) [3] . This appears to be an ambitious and welcome objective. Today, COVAX faces criticism mostly for the delays experienced by the implementation of its vaccination program. Indeed, as UNICEF shows [2] , COVAX has shipped up to 68.8 million doses in 81 of the 92 LMICs, indicating delivery of only 3.8% of the promised 1.8 billion doses. Till now, eleven LMICs have not received any doses from COVAX. The main reasons for such a failure are however external to COVAX, and related to supply side issues like over-procurement by high income countries [4] , or vaccine and vaccine material export restrictions imposed by high-income countries (HICs) like the US [5] , leaving few stocks for LMICs. As the vaccination rates in HICs sits at about 40% [6] , there is reason to be hopeful that COVAX will be able to support LMICs in time. Here, we argue that COVAX should anticipate additional challenges with regard to sanctioned countries. Currently, the UN, US and EU and others impose sanctions on over 20 countries around the world. While some of these sanctions are highly targeted in nature (such as arms embargoes, travel bans and individual asset freezes), and thus unlikely to influence certain countries' access to the vaccine, others represent de-facto comprehensive sanctions regimes, whose return results from the multiplying effect of overlapping sanctions regimes (sometimes alongside counterterrorism and anti-moneylaundering regulations), the adoption of broad sectoral sanctions (including those on finance and energy sectors in a dozen of countries) and the growing reluctance seen in the international banking sector to service transactions to so-called "high-risk" countries (known as over-compliance or 'de-risking') even for vaccine procurement. While COVAX assumes that all LMICs will be able to procure 70% of the remaining doses, it has thus ignored the three specific difficulties that sanctioned countries run into when they seek to procure such type of goods. First, COVAX may experience problems when delivering the vaccine to sanctioned countries, such as Iran, North Korea, Syria, Venezuela, Afghanistan and Myanmar, due to hindered access to goods and services including temperature-controlled equipment, fuel, software, insurance or logistics operators. Relatedly, COVAX may not be able to deliver or administer vaccines to certain groups within Open Access *Correspondence: gregoire.mallard@graduateinstitute.ch 3 Graduate Institute of International and Development Studies, Geneva, Switzerland Full list of author information is available at the end of the article de-risked countries, such as members of designated terrorist organisations (like Hezbollah) and other non-state armed groups. Second, most sanctioned countries are not in a position to procure the remaining 70% of the COVID vaccines. Exporters or their banks may not authorize the transactions with them, again due to de-risking. After a wave of heavy sanctions enforcement actions by the US Treasury, seeing global banks paying fines entering into the billions of US dollars, all global banks increasingly avoid any transactions with US-sanctioned countries, like Iran and Venezuela [7] . UNICEF data [8] shows that while non-sanctioned countries directly purchase from multiple suppliers, global pharmaceutical companies declined the sales to sanctioned countries: none of them signed a supply agreement with Syria, Afghanistan, North Korea, Venezuela or Iran, and only one supplied to Myanmar but only for 25% of the population. Third, bilateral donations, sometimes described as "vaccine diplomacy", have been delivered to some sanctioned countries by donors. It may make the impression in the international community that COVAX should concentrate on servicing the non-sanctioned developing countries and leave the delivery of vaccines to sanctioned countries to big powers. UNICEF data (Table 1) indicates that major economies, such as China, India, the US, Japan, Russia, and France are active in bilateral donations to specific countries, but the recipients are not those in most urgent humanitarian need. Because of these three reasons, we estimate that in 2 years, with COVAX setting a target of procuring 30% of the needed vaccines in LMICs, about 60 to 70% of the adult population in the non-sanctioned developing countries could be vaccinated, but that less than 20% of the total adult population will be vaccinated in the sanctioned developing world. We thus urge COVAX to rethink its targets and set two different kinds of programmes depending on whether LMICs face risks of financial exclusion because of sanctions. For those, COVAX needs to provide a higher percentage of the vaccines. Otherwise, the problems of vaccination will linger, risking the advent of new variants and preventing an effective global response in reigning the pandemic under control. UNICEF (UN Children Foundation), the Coalition for Epidemic Preparedness Innovations (CEPI), and the World Health Organization (WHO) convenient online submission • thorough peer review by experienced researchers in your field • rapid publication on acceptance • support for research data, including large and complex data types • gold Open Access which fosters wider collaboration and increased citations maximum visibility for your research: over 100M website views per year • At BMC, research is always in progress. Learn more biomedcentral.com/submissions Ready to submit your research Ready to submit your research ? Choose BMC UNICEF Covid-19 vaccine market dashboard. Delivery, COVAX deliveries GAVI. 92 low-and middle-income economies eligible to get access to COVID-19 vaccines through Gavi COVAX AMC (Advance Market Commitment) Amnesty: rich countries have bought too many COVID-19 vaccines US Presidential Executive Orders (EO) Bloomberg COVID vaccine tracker Reuters. Iran blames U.S. sanctions for vaccine payment problems UNICEF Covid-19 vaccine market dashboard. Agreements, Country/ group Note: MTN Group is a private company with leading telecom services in many African countries Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations