key: cord-0887223-k3q5kjud
authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj
title: Vulvar Aphthous Ulcer and COVID-19 mRNA Vaccination
date: 2021-12-31
journal: J Pediatr Adolesc Gynecol
DOI: 10.1016/j.jpag.2021.11.010
sha: b9a73872fb0a9edfcb32b0d8df8fd79786985b80
doc_id: 887223
cord_uid: k3q5kjud

nan

Dear Editor, we would like to share ideas on "Vulvar Aphthous Ulcer Following Pfizer-BioNTech COVID-19 Vaccine -A Case Report [1] ." Drucker et al. concluded that "Summary and conclusion-Vaccination, in general, has been associated with….caused by a similar mechanism and should be considered a rare side effect of this vaccine. [1] ." Mucocutaneous effect of COVID-19 vaccination is possible. The pathogenesis is still inconclusive. For post CPVOD-10 vaccination vulvar apthous ulcer, it is necessary for further investigation and monitoring of clinical symptom. The genital ulcer might be the first presentation of Behcet's disease and Behcet's disease is a rare problem observed following COVID-19 vaccination [2] .

For a possible pathogenesis, COVID-19 vaccination can induce a hyperviscosity problem [3] and hyperviscosity is a rare but possible clinical problem associated with Behcet's disease [4] .

Vulvar Aphthous Ulcer Following Pfizer-BioNTech COVID-19 Vaccine -A Case Report

Behcet's-like adverse event or inaugural Behcet's disease after SARS-CoV-2 mRNA-1273 vaccination? Rheumatology (Oxford)

Expected Viscosity After COVID-19 Vaccination, Hyperviscosity and Previous COVID-19

Haemorheological alterations in Behcet's disease are not related to a tendency for venous thrombosis

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