key: cord-0886499-6u91hb22 authors: Wang, Yadong; Xu, Jie; Wang, Ying; Hou, Hongjie; Shi, Li; Yang, Haiyan title: Prevalence of comorbid tuberculosis amongst COVID‐19 patients: A rapid review and meta‐analysis date: 2021-10-20 journal: Int J Clin Pract DOI: 10.1111/ijcp.14867 sha: c1dc4174ca9c542da904d6921fe39d84f3692010 doc_id: 886499 cord_uid: 6u91hb22 nan were used: "prevalence" or "incidence" or "rate" or "characteristics" and "tuberculosis" and "COVID-19" or "SARS-CoV-2" or "2019-nCoV" or "severe acute respiratory syndrome coronavirus 2" or "coronavirus disease 2019" or "2019 novel coronavirus". All peerreviewed papers which were published in the English language were eligibly included if they provided the incidence rate of comorbid tuberculosis amongst COVID-19 patients. Accordingly, we excluded case reports, review articles, duplicate publications, errata, comments and preprints. Reference lists of the retrieved articles were also screened to identify additional studies. This rapid systematic review and meta-analysis was performed following the guidelines of the Preferred Reporting Items for Systematic Reviews and Metaanalyses (PRISMA). 6 The pooled prevalence of comorbid tuberculosis amongst COVID-19 patients was estimated using a random effects metaanalysis model. 7, 8 The statistical heterogeneity across studies was assessed by I 2 statistic and Cochrane Q test. 9, 10 The risk of publication bias was evaluated by Begg's rank correlation test. 11, 12 All statistical analyses were carried out using the package "meta" on R version 3.6.3 (R Foundation for Statistical Computing). A two-tailed P value <.05 was regarded statistically significant. Table 1 . Overall, our findings demonstrated that the prevalence of comorbid tuberculosis amongst COVID-19 patients in this pooled meta-analysis was 1.6% with 95% confidence interval (CI): 1.3%-1.9% (Figure 1 ). The regional tuberculosis prevalence in In conclusion, our findings demonstrated that the prevalence of comorbid tuberculosis amongst COVID-19 patients was 1.6%, which varied greatly in different regions. The funders have no role in the data collection, data analysis, preparation of manuscript and decision to submission. 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