key: cord-0884826-liv733eg
authors: Tekin, Rojbin Ceylan; Gökhaner, Yurdagül Tolu; Tekin, Recep
title: Acute hemorrhagic encephalitis in a pregnant woman with coronavirus disease-2019
date: 2022-04-08
journal: Rev Soc Bras Med Trop
DOI: 10.1590/0037-8682-0630-2021
sha: dcec81c91f9392ae7b0dc947bc4a9873c8bdb94b
doc_id: 884826
cord_uid: liv733eg

nan

Rojbin Ceylan Tekin [1]  , Yurdagül Tolu Gökhaner [1]  and Recep Tekin [2]  [1] . Mardin State Hospital, Department of Radiology, Diyarbakir, Turkey. A 32-year-old pregnant woman with a 12-day history of fever and cough was admitted to the emergency department for confusion and severe headache at 24 weeks of gestation. She reported a worsening condition for 5 days with headache, confusion, and dyspnea. Neurological examination showed dysarthria and mild hemihypoesthesia. A polymerase chain reaction test from the nasopharyngeal swab confirmed the diagnosis of coronavirus disease (COVID-19). Chest computed tomography (CT) scan was also highly suggestive of COVID-19. The unenhanced axial and coronal reformatted thorax CT image demonstrates peribronchovascular and subpleural groundglass opacities and vascular dilatation (arrows) in the bilateral lung (Figure 1) . Magnetic resonance imaging (MRI) of the brain showed bilateral periventricular, thalamic, parahippocampal, and mesencephalic lesions with hyperintensity in FLAİR and T2WI, internal hemorrhage that caused susceptibility changes in SWI images (Figure 2) . In this case, the baby was delivered by cesarean section. The patient developed hypoxic respiratory failure and progressed to severe acute respiratory distress syndrome on day 12 and required intubation and mechanical ventilation under heavy sedation. Pregnant women with COVID-19 are more likely to have a preterm birth. Acute hemorrhagic encephalitis (AHE) is a rare and often fatal neurological complication of COVID-19 1,2 . AHE should be considered in the differential diagnosis of patients presenting with neurological symptoms in patients with COVID-19 3 . High clinical suspicion and early imaging diagnosis of this condition can enable clinicians to pursue more aggressive treatment options to reduce fatal outcomes. a b c

Case series of four pregnant women with COVID-19 in

Acute haemorrhagic leukoencephalitis (Hurst disease) in severe COVID-19 infection

A Rare Case of Acute Hemorrhagic Leukoencephalitis in a COVID-19 Patient