key: cord-0884750-h3yweijv
authors: Sookaromdee, Pathum; Wiwanitkit, Viroj
title: Effectiveness of mRNA Covid-19 vaccine in healthcare workers
date: 2021-09-06
journal: Enferm Infecc Microbiol Clin
DOI: 10.1016/j.eimc.2021.08.005
sha: dc617e52f05bf504a4edba8f3b74fad13585b322
doc_id: 884750
cord_uid: h3yweijv

nan

Dear Editor, we would like to discuss on publication entitled ". Effectiveness of the BNT162b2 mRNA Covid-19 vaccine in Spanish healthcare workers [1] ." 1. Núñez López et al. concluded that "BNT162b2 mRNA COVID-19 vaccine is highly effective in Spanish HCW [1] ." We agree that mRNA vaccine might be useful. However, it might be difficult to say that the vaccine is highly effective. Without laboratory investigation on protective antibody titer, the data on incidence of disease might be only indirect clinical evidence. The infection incidence might be associated with many factors including situation of disease epidemic, which is different at different time period. Without an investigation, it is not possible to detect the silent asymptomatic infection among HCW. In a setting the zero COVID-19 case in hospital, the positivity among HCW is still possible.

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La Paz Health Care Workers Vaccination Study Group

Effectiveness of the BNT162b2 mRNA Covid-19 vaccine in Spanish healthcare workers

Seroprevalence of hospital staff in a province with zero COVID-19 cases