key: cord-0882616-t2r4g5ky authors: nan title: Children may be less affected than adults by novel coronavirus (COVID‐19) date: 2020-04-20 journal: J Paediatr Child Health DOI: 10.1111/jpc.14876 sha: 3dda656b879c7266c609b03c603b512ca8061490 doc_id: 882616 cord_uid: t2r4g5ky nan Children may be less affected than adults by novel coronavirus (COVID-19) COVID-19 is a new strain of coronavirus that has infected people from many countries around the world. Initial reports suggest that children are relatively spared by this virus in comparison to adults. The February 2020 World Health Organization-China Joint Mission on Coronavirus Disease 1 found that only 2.4% of cases were in those less than 19 years of age. Furthermore, disease severity was less in infected children compared to the total infected population; only 2.5% of children developed severe disease (compared to 13.8% overall) and 0.2% of children developed critical disease (compared to 6.1% overall). Severe disease was defined as dyspnoea, tachypnoea, hypoxia or infiltrates affecting >50% of the lung fields within 48 h, and critical disease was defined as respiratory failure, septic shock and/or multi-organ failure. Although reported case numbers are quite small, young infants seem to have relatively low rates of being severely affected; one study of nine infected infants found none required intensive care or had significant complications. 2 Despite this, certain paediatric populations, such as extremely prematurely born babies, are likely to be particularly vulnerable, with one death confirmed in this subgroup. 3 Further evidence is likely to emerge with time on just how children as a cohort globally will fare with this epidemic illness. HPV Vaccination Impact Study Group. Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: Updated systematic review and meta-analysis Impact of HPV vaccination and cervical screening on cervical cancer elimination: A comparative modelling analysis in 78 low-income and lower-middle-income countries World Health Organization. World Health Organization-China Joint Mission on Coronavirus Disease Novel coronavirus infection in hospitalized infants under 1 year of age in China Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia