key: cord-0881552-8jqn17lt
authors: Mehta, Salil; Nagvekar, Vasant; Gupta, Garima
title: Utility of 2-Deoxy-2-[18F]fluoro-Dglucose positron emission tomography/computed tomography scan in the systemic evaluation of patients with post-COVID-19 endogenous presumed fungal endophthalmitis
date: 2021-09-25
journal: Indian J Ophthalmol
DOI: 10.4103/ijo.ijo_1784_21
sha: 8853189cb329638c3f6e525acd399c008f64de04
doc_id: 881552
cord_uid: 8jqn17lt

nan

A 48-year-old nondiabetic male presented with persistent breathlessness, cough, intermittent pyrexia, and grossly reduced vision in the right eye. Based on the available records, he had been diagnosed with COVID-19 earlier (based on a positive RT-PCR) and had received domiciliary care for an initial five days. Following clinical deterioration, he was admitted, treated with systemic steroids, antibiotics, and ventilatory support. Ten days post discharge, he developed a gross reduction in vision in the right eye (CF: 1 m). Five days later, he underwent a vitrectomy for endophthalmitis with intravitreal voriconazole (100 mcg), vancomycin (1 mg), and ceftazidime (2.25 mg) with a reported postoperative vision of 6/24 (20/80). Microbiology of the vitreous fluid for KOH, gram staining, and culture/sensitivity were reported as negative.

He was readmitted in our tertiary care center on the 14 th day postoperatively. On admission, he was afebrile, with tachycardia (heart rate: 91/min), dyspneic (respiratory rate: 21/minute) with inspiratory basilar crackles with decreased air entry bilaterally. His oxygen saturation was normal (99%). The visual acuity was HMCF in the right eye and 6/6 (20/20) in the left eye. Dilated fundus exam showed significant vitreous haze (3+) that obscured the fundus view [ Post-COVID-19 endogenous endophthalmitis is increasingly being recognized, and identification of the systemic focus and its treatment is an integral part of treatment. [1] Fungal endophthalmitis due to mucor species has only rarely been reported. [2] The use of a FDG PET/CT scan allowed identification of a pulmonary focus and suggested potential sites of biopsy, thus increasing the possibility of a positive diagnosis.

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/ their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Nil.

There are no conflicts of interest. 

Retinal manifestations in patients following COVID-19 infection

Unilateral rhino-orbital-cerebral mucormycosis with contralateral endogenous fungal endophthalmitis