key: cord-0877048-hr8w4on7 authors: Ong, Mei-Sing title: Socioeconomic status and survival in patients with pulmonary hypertension date: 2020-11-10 journal: ERJ Open Res DOI: 10.1183/23120541.00638-2020 sha: 26ccd1a8dc3856fad1bdd999409e272a26781db7 doc_id: 877048 cord_uid: hr8w4on7 In a publicly funded healthcare system, no evidence of survival disparities across socioeconomic classes among patients with pulmonary hypertension was observed, underscoring the importance of eliminating financial barriers to medical care and treatment https://bit.ly/2Eb1ju2 healthcare and medical treatment are free at the point of delivery, the USA and China do not have universal health insurance coverage. In the USA, a substantial number of residents remain uninsured; even among those who are insured, insurance coverage of medical services and treatments varies widely, and are often accompanied by high out-of-pocket costs. The high cost of pulmonary hypertension therapy can be a barrier to treatment access for the uninsured. Although many factors confound cross-national comparisons, published studies in the USA and other countries have consistently shown that uninsured individuals have poorer health and life expectancy than insured individuals, and expansion of health insurance coverage reduces mortality burden in the most vulnerable populations [10] [11] [12] [13] [14] . Financial barriers to medical treatment are, however, only one of many drivers of health inequities. Disparities in health among socioeconomic classes have also been reported in healthcare systems where access to care is presumably universal [15, 16] . How much of the better health of the privileged is accounted for by better access to healthcare remains difficult to quantify. In Scotland, published studies reported disparities in health outcomes across a range of conditions, including cancer [17] , cardiovascular disease [18, 19] and type 1 diabetes [20] . What differentiates the current study may be that treatment of pulmonary hypertension in Scotland is only available at one centre to which all patients in the country with pulmonary hypertension are referred. As highlighted by PELLINO et al. [8] , this centralisation of care enhances the likelihood of care uniformity regardless of a patient's postcode. In most other settings, socioeconomically disadvantaged individuals are more likely to receive care at medical centres with fewer resources available to provide high-quality care, and greater access to high-quality hospitals offsets socioeconomic disparities in survival for a range of conditions [21] . Any observational study is susceptible to confounding by indication and the results of the current study need to be interpreted in the light of several limitations. First, referral bias may have led to fewer socioeconomically disadvantaged patients being seen at the SPVU. The authors attempted to address this potential bias by comparing the distribution of social deprivation status among the study cohort against the general population in Scotland. The comparison showed no differences, which is reassuring. Second, the current study uses the SIMD, an area-based social deprivation indicator, as a proxy for individual socioeconomic status. Although area-based measures can meaningfully capture socioeconomic context at the neighbourhood scale, it cannot identify whether individuals or households are experiencing deprivation. A study evaluating the SIMD showed that the proportion of deprived individuals within areas designated as deprived varies widely across different regions [22] . When applied to a relatively small study cohort, this limitation may not be negligible [23] . Third, the effects of socioeconomic status on health outcomes can vary substantially by population groups not accounted for in the current study. Most notably, racial and ethnic minorities often experience undesirable health outcomes. Although members of minority populations are disproportionately more likely to have low socioeconomic status, published studies have shown that race and ethnicity are independent predictors of poor health outcomes. For example, a USA-based study found that pregnancy-related mortality rate for black women with at least a college degree was 1.6 times that of white women with less than a high school diploma and five times that of white college-educated women [24] . Racial disparities in health outcomes have also been documented in Scotland [25] [26] [27] . The association of race/ethnicity and survival in pulmonary hypertension is less well understood. Most evidence to date points to a trend towards increased mortality among minority races compared with white people [28] [29] [30] ; however, data from the REVEAL registry demonstrated a higher mortality risk among white people compared with minority races [31] . Racial and ethnic disparities are arguably the most obstinate inequities in health over time, driven by long-standing systemic social inequities. A closer look at the interactions between socioeconomic status and race/ethnicity will allow for more robust explanations of the patterns of disparities. The pathways through which socioeconomic status affect healthcare are complex. Nonetheless, the consequences of socioeconomic status on health are modifiable by policies. Although more research is needed to understand the influence of socioeconomic status on survival in pulmonary hypertension, the study by MCGETTRICK et al. [7] offers an encouraging example of how providing equal access to healthcare can potentially help address survival disparities in a high-morbidity disease. The current COVID-19 pandemic has laid to bare the widespread societal consequences of health inequities. In this time of worsening socioeconomic conditions and rising inequality, widening disparities could result. The importance of addressing health inequities and disparities cannot be overstated. 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