key: cord-0871746-tzhay70i
authors: Yamanyar, Gulcin Koc; Halacli, Burcin; Yildirim, Mehmet; Topeli, Arzu
title: Neurological complications during the course of severe COVID-19: is it just the tip of the iceberg?
date: 2022-02-22
journal: Acute Crit Care
DOI: 10.4266/acc.2021.01445
sha: 31634ea09469921dd350dec784824a894112e007
doc_id: 871746
cord_uid: tzhay70i

nan

patients. Although many studies have been published to reveal the relationship between COVID-19 and stroke, the majority of patients with IS during COVID-19 have advanced age and co-morbidities similar to our patients [4, 5] . In a study of a high-volume center examining the relationship between COVID-19 and stroke, usual causes of stroke were found in most of the stroke cases. Moreover, all patients with an acute stroke without a usual etiology presented a severe infection requiring mechanical ventilation [5] . We believe that detailed etiological evaluations will give more accurate results in terms of determining COVID-19 related neurological complications. Therefore, more studies are needed to define the real incidence of neurological complications of COVID-19 and to clarify the underlying mechanism and causality between COVID-19 and neurological diseases.

Neurological manifestations of COVID-19: a systematic review and current update

6-Month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

Frequency of neurologic manifestations in COVID-19: a systematic review and meta-analysis

Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study

COVID-19 and stroke: incidence and etiological description in a high-volume center

No potential conflict of interest relevant to this article was reported.