key: cord-0866291-wwbcv1kx authors: Stanaway, Fiona; Irwig, Les M; Teixeira‐Pinto, Armando; Bell, Katy JL title: COVID‐19: estimated number of deaths if Australia had experienced a similar outbreak to England and Wales date: 2021-01-13 journal: Med J Aust DOI: 10.5694/mja2.50909 sha: 2763b0d7ca634d4d747b8e3512675169d6582164 doc_id: 866291 cord_uid: wwbcv1kx nan To the Editor: Australia has had a remarkably successful response to coronavirus disease 2019 (COVID-19), even considering the second wave experienced in Victoria. The Australian rate of COVID-19-related deaths of 35 per million population is 15-20 times lower than that observed in countries across Europe and the Americas. 1 However, as the second wave in Melbourne has shown, it is important not to become complacent. Using all-cause mortality data in England and Wales over the peak of the COVID-19 outbreak in March and April 2020, we directly estimated the number of excess deaths that might have occurred if the outbreak in Australia had been of a similar extent to that in England and Wales. We estimated the relative risk of all-cause mortality in England and Wales from the COVID-19 outbreak by dividing the total deaths from all causes for weeks 11-21 in 2020 (9 March -24 May) by the mean number of deaths for the weeks 11-21 averaged over 5 years (2014-2018) (limited to years when comparable Australian data were available). We calculated age and sex stratified relative risks as there are well documented differences in COVID-19 fatality by age and sex. 2 To estimate the baseline risk of all-cause mortality in the Australian population, we estimated the mean number of deaths by age and sex for weeks 11-21 over the period 2014-2018. Finally, to estimate the total deaths that might have occurred if Australia had experienced a similar outbreak to England and Wales, we multiplied the baseline expected number of deaths by the agespecific relative risks for men and women (Box). This resulted in an estimated additional 16 313 deaths in Australia: 9295 men and 7018 women. In contrast, by 26 May 2020 there had been 102 COVID-19-attributed deaths in Australia and 1365 excess total deaths from weeks 11 to 21 according to provisional mortality statistics. 3 This enormous difference underlies the importance of Australia's response using a combination of extensive testing and contact tracing, mandatory quarantine of people returning from overseas, and shutdowns to control community transmission. While acknowledging that these measures carry with them substantial social and economic harms, we wish to highlight the scale of the loss of life avoided. Further details of our methods and results are available in InSight+. 4 Australian COVID-19 response may have saved 16 000 lives The fees for deaths data from the