key: cord-0865766-d6nplxby
authors: Schenker, Hannah M; Hagen, Melanie; Simon, David; Schett, Georg; Manger, Bernhard
title: Reactive arthritis and cutaneous vasculitis after SARS-CoV-2 infection
date: 2020-11-18
journal: Rheumatology (Oxford)
DOI: 10.1093/rheumatology/keaa689
sha: 0ea29eb0376347137652ff818696131f983c91b3
doc_id: 865766
cord_uid: d6nplxby

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still exhibited antiviral reactivity, suggesting the presence of a very strong humoral immune response in this case. All clinical symptoms and CRP levels immediately regressed after initiating prednisolone.

While there is no evidence that these phenomena were caused by COVID-19, it appears the most likely scenario after ruling out other likely causes. The timely relation, presence of HLA-B27 as well as the strong anti-SARS-CoV-2 IgG antibody response support the concept that COVID-19 induced an autoimmune response that led to reactive arthritis and vasculitis.

Funding: No specific funding was received from any funding bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article.

Disclosure statement: The authors have declared no conflicts of interest.

Data are available upon reasonable request by any qualified researchers who engage in rigorous, independent scientific research, and will be provided following review and approval of a research proposal and Statistical Analysis Plan (SAP) and execution of a Data Sharing Agreement (DSA). All data relevant to the study are included in the article.

Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirusinfected pneumonia in Wuhan, China