key: cord-0856474-05x4cc4f authors: Rrapi, Renajd; Chand, Sidharth; Lo, Jennifer A.; Gabel, Colleen K.; Song, Sarah; Holcomb, Zachary; Iriarte, Christopher; Moore, Kevin; Shi, Connie R.; Song, Hannah; Di Xia, Fan; Yanes, Daniel; Gandhi, Rajesh; Triant, Virginia A.; Kroshinsky, Daniela title: The Significance of Pressure Injuries and Purpura in COVID-19 Patients Hospitalized at a Large Urban Academic Medical Center: A Retrospective Cohort Study date: 2021-03-20 journal: J Am Acad Dermatol DOI: 10.1016/j.jaad.2021.03.051 sha: 0837b9b9448b09859ffed4288b34c0a9befb4b59 doc_id: 856474 cord_uid: 05x4cc4f nan impact quality of life, are associated with increased mortality, and result in increased healthcare 34 costs. 1 In COVID-19 infection, sites of pressure injury have been associated with purpuric Table 1 ). The incidence of pressure injury in this study (6.9%) is comparable to previous estimates 52 of between 5% and 15% of hospitalized patients depending on clinical context. 1 With respect to 53 COVID-19 hospitalization specifically, the especially tenuous respiratory status in these 54 critically ill patients frequently interfered with standard preventative measures to turn patients for 4 patients had multiple pressure injuries of which some had purpuric features and others had only nonpurpuric features. Values for these patients are tabulated in both columns. 2 Statistical testing is performed comparing patients having pressure injuries with purpuric features to patients having pressure injuries none of which had purpuric features. Abbreviation: Standard deviation (SD); Body mass index (BMI). Pressure ulcers: Pathophysiology, epidemiology, risk 81 factors, and presentation Purpuric Ulcers Associated with COVID-19 Infection: A 85 Case-Series Challenges in the management of critical ill COVID -19 patients with 87 pressure ulcer Therapeutic strategies for critically ill patients with COVID-19. Annals of 89 Intensive Care COVID-19 and its implications for thrombosis and 91 anticoagulation