key: cord-0845561-2jw7qoek
authors: Au, Sunny Chi Lik
title: Central retinal artery occlusion in COVID-19
date: 2021-10-03
journal: Indian J Ophthalmol
DOI: 10.4103/ijo.ijo_1803_21
sha: 34eae9eed1930f99869d9b22df6034a8b5cb7e83
doc_id: 845561
cord_uid: 2jw7qoek

nan

Dear Editor,

We read with interest the review by Sen et al. titled "COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19". [1] We are particularly interested in the central retinal artery occlusion (CRAO) part, as our Hyperbaric Oxygen therapy for central Retinal Artery occlusion (HORA) study team provides round-the-clock hyperbaric oxygen therapy (HBOT) for CRAO cases even during the coronavirus disease 2019 (COVID-19) pandemic. [2] COVID-19-related CRAO is postulated to be a result of predisposition to arterial thrombosis in patients with the novel coronavirus infection. Given the arterial thrombosis is systemic, these patients might have associated cerebrovascular thrombotic stroke. As an update, bilateral COVID-19-related CRAO cases were reported. [3] By reviewing the literature, we can actually classify the COVID-19-related CRAO cases into two groups according to the presence of concomitant stroke. [4, 5] The case reports of Acharya et al. and Dumitrascu et al. mentioned in the original review, [1] together with the bilateral CRAO cases of Bapaye et al., were without any carotid or cerebrovascular thrombosis on radiological imaging. In contrast, Patients 10 and 8, respectively, in the Alam et al. [4] and Sweid et al. [5] case series got stroke in the territory of internal carotid artery supply.

Although CRAO is hypothesized to correlate with the COVID-19 infection, CRAO is a rare ocular disease to be investigated. Here, we present our HBOT treatment data on the incidence of COVID-19 among all acute CRAO patients in our territory-wide referral center. Since the time COVID-19 was declared as a pandemic, there were 28 acute CRAO patients in Hong Kong by the mid of June 2021. The average age was 68.5 years old (range 27-88), and 15 of them were males. None of them got severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detected on reverse transcription polymerase chain reaction by the validated Xpert Xpress SARS-CoV-2 assay. At their last follow-up, mean 8.2 ± 4.8 months (range 1-15), none got COVID-19 infection despite our locality experienced the fourth wave of COVID-19 attack.

Nil.

There are no conflicts of interest.

COVID-19 and Eye: A review of ophthalmic manifestations of COVID-19

Performing hyperbaric oxygen therapy for central retinal artery occlusion under COVID-19: From myringotomy to rapid viral test

Simultaneous bilateral central retinal artery occlusion following COVID-19 infection

Coronavirus positive patients presenting with stroke-like symptoms

Letter: Thrombotic neurovascular disease in COVID-19 patients

Cite this article as: Au SC. Central retinal artery occlusion in COVID-19

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