key: cord-0844503-0ou2pdf3
authors: Ghodsizad, Ali; Grant, April A.; Mirsaeidi, Mehdi; Sneij, Waleed C.; Khalid, Laiqua; Delazerda, David; Auerbach, Jonathan S.; Alvarez, Roger A.; de Marchena, Eduardo J.; Hare, Joshua; Guerra, Giselle; Vianna, Rodrigo; Loebe, Matthias
title: Management of crash and burn patients with SARS‐CoV‐2 associated ARDS
date: 2020-07-14
journal: J Card Surg
DOI: 10.1111/jocs.14699
sha: d1f179682ea1542534730902392adab8f1975cfd
doc_id: 844503
cord_uid: 0ou2pdf3

nan

To the Editor, In December 2019, China reported an outbreak of a new coronavirus in Wuhan, China. 1 Since then the number of SARS-CoV-2 positive patients has expanded exponentially over several continents in only a few weeks. The first case in the United States was diagnosed in February of 2020 and by mid-March there were over 400 000 positive cases, leading to a great strain on our health care system. 

Plasma from survivors has successfully been used to treat actively infected patients. Finding the appropriate number of donors is, of course, the challenging part.

As reported by others, we have also observed that the respiratory failure phenotype induced by the COVID-19 virus behaves differently than the acute respiratory distress syndrome we typically see in patients with other types of infectious pneumonia such as H1N1 or bacterial. They present with a Murray score > 3 usually which develops over several hours from a normal-looking chest X-ray. Proning has been shown to improve the oxygenation in this patient population. Patients who have not improved with proning have shown improvement in respiratory function after application of venovenous

Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan China: a retrospective cohort study

Inhibition of SARS-VoV-2 infections in engineered human tissues using clinical grade soluble human ACE2

A weaning protocol for venovenous extracorporeal membrane oxygenation with a review of the literature