key: cord-0840232-iej6hadq
authors: Schenck, Edward J.; Turetz, Meredith L.; Niederman, Michael S.
title: Letter from the United States: A New York experience with COVID‐19
date: 2020-07-05
journal: Respirology
DOI: 10.1111/resp.13893
sha: 9813728cd35caa3e6ebe94da397f6002aaf1f102
doc_id: 840232
cord_uid: iej6hadq

nan

The sudden emergence of coronavirus disease 2019 (COVID-19) has had a profound impact on the practice of pulmonary and critical care medicine (PCCM) at our hospital, in New York City, the epicentre of the pandemic in the United States. From 6 March through 15 May 2020, we treated 1246 hospitalized COVID patients, with 268 needing mechanical ventilation, and during that same time, we took care of countless outpatients with acute COVID-19 illness and its sequelae. 1 The sudden surge of severely ill patients in a narrow time window imposed great stress on our resources, our patients, their families and our providers. In the process of caring for these patients, we learned much, and many of the lessons and adaptations that we made will change the practice of PCCM for years to come, both in and out of the hospital. In addition, we are developing new methods for providing education, training and supervision, which will also have a lasting impact on the nature and methods of postgraduate education in PCCM.

As we have become aware of the need for social distancing, and many patients are wary of returning to traditional offices and hospital settings, telemedicine has become a central part of our new world. 2 In the outpatient setting, we are seeing fewer patients face-to-face, and relying more on video visits. Telemedicine provides access to medical care, without long wait times, and can allow us to accurately evaluate some common problems such as lung nodules, mild asthma, mild chronic obstructive pulmonary disease (COPD), cough and dyspnoea. We have also seen a large number of patients who are recovering from COVID-19 and have symptoms of cough, postinfectious bronchospasm, dyspnoea, post-COVID-19 organizing pneumonia and a variety of non-specific respiratory complaints, and many of these can be managed remotely. It is clear that outpatient practice will need to accommodate the care of patients who have recovered from COVID-19. This will include not only those who did not require hospitalization, but also those surviving intensive care unit (ICU) care, who need to recover from 'post-ICU syndrome', with a focus on not only respiratory illness, but also psychological distress, occupational limitations and physical reconditioning. While telemedicine has facilitated some patient contact, especially with those reluctant to leave their homes, there are limitations to this technology. Most obviously, we have a limited ability to do a thorough physical examination of the lung, but we also miss the intangible 'sixth sense' that an experienced clinician can employ when sitting with a patient during an evaluation. During a video visit, we cannot do lung function testing or other physiological evaluations such as the 6min walk test. Patient satisfaction with telemedicine is mixed, and in our experience, while patients find the visit to be acceptable, 60% have told us that they want their next visit to be done in person. We have worried that some patients without COVID-19 disease, but with other serious respiratory illnesses will avoid getting needed medical care, to their own detriment. Thus, going forward, we will need to find the right balance of in-person versus video visits, but after our recent experiences, it seems that telemedicine will be a permanent part of our practice. For the future, we anticipate that as many as half of all encounters will be by video, and that the frequency of being able to see complex patients may actually increase, using a mixture of in-person and video evaluations. For many patients, we may be able to alternate in-person with video visits, and optimize how closely we can monitor them .

The inpatient practice of PCCM will also be changed because of our experiences with COVID-19. Our entire concept of what defines an ICU and ICU team has changed. When we needed to develop 'pop-up ICUs' to handle a fiveto six-fold higher number of critically ill patients than could be handled in our usual number of ICU beds, we improvised and developed ICU in areas that were not previously configured for this purpose. This included areas originally designated for lower levels of care, or even converting operating rooms into ICU. 3 We improvised with non-traditional ventilators, usually used for noninvasive ventilation, chronic ventilation or even by adapting anaesthesia machines to accommodate the fivefold greater number of ventilated patients. We developed multidisciplinary ICU teams using a mixture of PCCM physicians, nurses, anaesthesiologists, cardiologists, emergency medicine physicians, neurointensivists, surgical intensivists and even hospitalists. With proper supervision, organization and camaraderie, all members of the team brought their own unique expertise. We also developed specialized teams to help with very specific tasks. Thus, we had an intubation team comprised of anaesthesiologists and nurse anaesthetists; a vascular access team comprised of surgical proceduralists; and a proning team comprised of physical therapists. This type of specialization is not our usual practice, but was essential with the high volume of procedures being done in a short time period, and may be needed in the future for new surges of critical illness.

Our experiences with COVID-19 taught us many new lessons about critical illness and specific aspects of disease management, which are likely to change our future practices. We had initially been reluctant to use high-flow oxygen and non-invasive ventilation, to forestall intubation, because of concern about transmitting viral infection. However, over time, we learned how to use these modalities in new ways, which sometimes helped us to avoid intubation in individual patients. We re-evaluated our understanding of hypoxaemic respiratory failure, and identified patients with traditional acute lung injury and non-compliant lungs, but also those with more compliant lungs with severe hypoxaemia and a possible pulmonary vascular disease component. 4 We have understood the multi-organ system dysfunction of COVID-19, with its coagulation, cardiac, cerebral and renal complications and this will heighten our awareness of similar complications in patients with other forms of critical illness. 5 Our understanding of acute lung injury mechanisms has evolved, with a renewed focus on 'cytokine storm' mechanisms of injury which has caused us to consider the timing of a variety of anti-inflammatory interventions including specific cytokine inhibitors (interleukin (IL)-1, IL-6 and others) and non-specific therapies such as corticosteroids. 6 In caring for COVID-19 patients, there was a great thought given to the optimal timing of tracheostomy from the perspective of patient benefit and staff infection risk. We generally waited 2-3 weeks before performing a tracheostomy, yet were often gratified to see that after the procedure, many patients were then successfully removed from heavy sedation and mechanical ventilation, lessons which we may be able to apply to other illnesses, going forward. Finally, our understanding of community-acquired pneumonia has changed, and it is likely that viral pneumonia will be an important focus of future studies, a direction in which we were already moving, as a result of prior pneumonia studies that showed an increasing importance of non-bacterial infection. 7 In our centre, medical education is a vital part of our mission and in PCCM, we have 13 dedicated postgraduate fellows who spend 3 years doing a combined fellowship in PCCM (which includes 18 months of protected research time), as well as two others doing research fellowships. To manage the care needed for COVID-19 patients, all fellows gave up research and education activities to focus on providing clinical care. Although this was necessary, it may become an ongoing need when future ICU surges occur, and may detract from the research productivity of those with an investigative focus. All of the events surrounding the COVID-19 response will affect future recruitment of trainees in PCCM. While the experience will help to more closely integrate pulmonary with critical care, it remains unclear if our discipline will have more or less appeal to younger physicians. On one hand, COVID-19 demonstrated the reward and satisfaction of providing care to the most ill, and the excitement of putting basic physiological and scientific principles to use at the bedside, adding to the excitement of the specialty. On the other hand, the time and emotional strain of providing care to these patients was overwhelming, and the lifestyle demands on these physicians may be discouraging to future trainees. Methods of learning will change, with many lectures and conferences now being held online, a trend that will likely grow, going forward. Our recruitment process itself will change, with onsite tours and interviews being replaced by virtual exploration and online interviews. This new process may make it harder for institutions and applicants, to identify the best trainees and programmes, respectively. Finally, our trainees have been particularly prone to emotional 'burnout' during the care of multiple seriously ill patients. 8, 9 Future educational programmes will need to continue to focus on work/life balance and support of emotional needs to prevent burnout, so that trainees can feel supported as they grow into their roles in their new specialty. In New York, COVID-19 has led to a massive upheaval in many aspects of our specialty, and it is now our joint responsibility to learn from the experiences we have had, and transform our field for the good of patient care and the education of our future leaders (Table 1) 

Clinical characteristics of Covid-19 in

Virtually perfect? Telemedicine for Covid-19

Hospital preparedness for COVID-19: a practical guide from a critical care perspective

Respiratory mechanics and gas exchange in COVID-19 associated respiratory failure

Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19

COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal

Communityacquired pneumonia requiring hospitalization among U.S. adults

Preventing a parallel pandemic -a national strategy to protect clinicians' well-being

Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019