key: cord-0836333-htukhseq
authors: Sadeghi, Mohammad Reza
title: Does Lack of Vertical Transmission of COVID-19 Guarantee the Health of the Fetus or Neonate in Infected Mothers?
date: 2020
journal: J Reprod Infertil
DOI: 10.18502/jri.v21i4.4323
sha: db8e26e0e2ac2e7fa1d71b449387a50dd287397c
doc_id: 836333
cord_uid: htukhseq

nan

outcomes in neonates. In addition, the association between maternal immune activation-induced autism and schizophrenia has been well established through epidemiological studies and animal models (3) .

Therefore, the effect of this virus on people in different age, sex and ethnic groups and even on different organs of an infected person is unknown and every day new symptoms and complications of this disease are reported. Due to the lack of knowledge about its effects on the fetus, neonates, and infected mothers, pregnancy should be delayed as much as possible. At the same time, by conducting more studies, our knowledge can be consolidated regarding the short and long-term effects of this virus on both mother and fetus during pregnancy. Currently, published studies with small sample size are often performed on infected women at late phases of pregnancy (Third trimester). Therefore, special attention should be paid to early stages of pregnancy, during which the virus affects the placental functions with subsequent risks for the fetus. In addition, further research on the inflam-matory disorders in pregnant women with SARS-CoV-2 and longitudinal studies on newborns, exposed to the virus directly or indirectly, are required to ensure proper care of infected pregnant women and their newborns. It seems the coronavirus will be with us for many years to come, and we need to know more about living with this unknown virus with maximum protection and suppress its harmful effects.

Coronavirus disease 2019 in pregnancy

Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening

COVID-19 in pregnancy: placental and neonatal involvement

Evidencenfor and against vertical transmission for severe acute respiratory syndrome Coronavirus 2

COVID-19: neurological considerations in neonates and children

COVID-19 during pregnancy: potential risk for neurodevelopmental disorders in neonates?