key: cord-0836286-5xuahjoq authors: Patel, Nishil; Kho, Jason; Smith, Kirsty E.; Ahmed, Alia; Van den Abbeele, Koenraad; Mandal, Amit K. J.; Missouris, Constantinos G. title: Polymorphic cutaneous manifestations of COVID‐19 infection in a single viral host date: 2020-07-19 journal: Int J Dermatol DOI: 10.1111/ijd.15072 sha: 5a0ebe660c506a3e94ee07bc2619375409284cee doc_id: 836286 cord_uid: 5xuahjoq nan Over the next 24 hours, she developed intermittent pyrexia up to 38.4°C but remained clinically stable. There was associated anorexia and lassitude without any respiratory symptoms. A week previously, the patient's daughter had noticed a widespread non-pruritic, erythematous blanching maculopapular eruption which appeared on the trunk. There was evidence of vesicles and urticaria consistent with a viral exanthem. The daughter also reported facial angioedema with drooling and throat discomfort but without stridor. In addition, there was a malar distribution rash of similar morphology. These lasted for 2 days (Fig. 1a-c) . On Day 4, the rash progressed to a purpuric appearance (Fig. 1d) . Skin examination on Day 6 (admission Day 1) revealed hyperpigmented patches residual of the previous erythematous rash with surrounding scaling and flaking (Fig. 1e) . Extended autoimmune and viral screens were found nega- Our patient demonstrated three or more of the recognized patterns: vesicular eruptions, urticarial lesions, and papules which evolved to a purpuric appearance. These lasted for at Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Cutaneous manifestations in COVID-19: a first perspective Endothelial cell infection and endotheliitis in COVID-19 Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Angioedema in COVID-19 Funding source: None. doi: 10.1111/ijd.15072