key: cord-0834955-tfzz5prp
authors: Kuno, Toshiki; So, Matsuo; Miyamoto, Yoshihisa; Iwagami, Masao; Takahashi, Mai; Egorova, Natalia N.
title: The association of COVID‐19 antibody with in‐hospital outcomes in COVID‐19 infected patients
date: 2021-08-12
journal: J Med Virol
DOI: 10.1002/jmv.27260
sha: 81277e3b3e93ecc9791de721c305b7fbc2de1258
doc_id: 834955
cord_uid: tfzz5prp

We aimed to investigate whether hospitalizations of patients who tested positive for coronavirus disease 2019 (COVID‐19) antibodies are associated with reduced in‐hospital mortality. Of the 2459 patients admitted due to COVID‐19 and tested for antibodies, 937 (38.1%) had positive tests. After adjustment for patient characteristics and treatments, patients with positive COVID‐19 antibody test had lower in‐hospital mortality compared with those with negative test results (odds ratio [OR]: 0.62; 95% confidential interval [95% CI] 0.46–0.83, p = 0.001). In conclusion, positive COVID‐19 antibody test results were associated with the reduced risk of in‐hospital mortality for COVID‐19 patients.

T A B L E 1 Baseline characteristics of patients admitted with COVID-19 stratified by COVID-19 antibody In the subgroup analyses, the positive antibody was associated with decreased risk of in-hospital mortality for patients with endotracheal intubation and hypoxia ( Table 2) .

The recent observational study demonstrated that COVID-19

antibody decreased the risk of reinfection. 2 

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The association of COVID-19 antibody with in-hospital outcomes in COVID-19 infected patients

waiver of patients' informed consent was also approved by the institutional review boards.

Research data are not shared.