key: cord-0832218-tmd7p5zd
authors: Priyanka; Choudhary, Om Prakash; Singh, Indraj
title: Protective immunity against COVID-19: Unravelling the evidences for humoral vs. cellular components
date: 2020-11-10
journal: Travel Med Infect Dis
DOI: 10.1016/j.tmaid.2020.101911
sha: a2ab99be199359506d6e02b96d807f51f1ee3f18
doc_id: 832218
cord_uid: tmd7p5zd

nan

these loci need to be identified as biomarkers of immunological protection. protective immunity. In an outbreak with 85 percent attack rate, the neutralizing antibodies 44 from previous SARS-CoV-2 infection were significantly associated with protection against 45 re-infection (also observed in animal models like rhesus macaques) [3] . IgG against the 46 receptor-binding domain of spike protein have high specificity and sensitivity and sustain in patients up to 75 days [3] . Another study deciphered that neutralizing antibodies decline lasting protection against Covid-19. Dental Tribune 2020. 

Humans develop robust immune response & memory that may provide

Clinical 145 and immunological assessment of asymptomatic SARS-CoV-2 infections

Lessons for COVID-19 immunity from other coronavirus 148 infections

Coronavirus disease 2019 (COVID-19) Re-153 infection by a phylogenetically distinct severe acute respiratory syndrome coronavirus 154 2 strain confirmed by whole genome sequencing