key: cord-0828023-smtc4n03 authors: Ali, Amira Mohammed; Al-Amer, Rasmieh; Kunugi, Hiroshi; Stănculescu, Elena; Taha, Samah M.; Saleh, Mohammad Yousef; Alkhamees, Abdulmajeed A.; Hendawy, Amin Omar title: The Arabic Version of the Impact of Event Scale-Revised: Psychometric Evaluation among Psychiatric Patients and the General Public within the Context of COVID-19 Outbreak and Quarantine as Collective Traumatic Events date: 2022-04-24 journal: J Pers Med DOI: 10.3390/jpm12050681 sha: 044185f4d664dc4cb0cc8d7c9092b8a1830ad6d9 doc_id: 828023 cord_uid: smtc4n03 The Coronavirus Disease-19 (COVID-19) pandemic has provoked the development of negative emotions in almost all societies since it first broke out in late 2019. The Impact of Event Scale-Revised (IES-R) is widely used to capture emotions, thoughts, and behaviors evoked by traumatic events, including COVID-19 as a collective and persistent traumatic event. However, there is less agreement on the structure of the IES-R, signifying a need for further investigation. This study aimed to evaluate the psychometric properties of the Arabic version of the IES-R among individuals in Saudi quarantine settings, psychiatric patients, and the general public during the COVID-19 outbreak. Exploratory factor analysis revealed that the items of the IES-R present five factors with eigenvalues > 1. Examination of several competing models through confirmatory factor analysis resulted in a best fit for a six-factor structure, which comprises avoidance, intrusion, numbing, hyperarousal, sleep problems, and irritability/dysphoria. Multigroup analysis supported the configural, metric, and scalar invariance of this model across groups of gender, age, and marital status. The IES-R significantly correlated with the Depression Anxiety Stress Scale-8, perceived health status, and perceived vulnerability to COVID-19, denoting good criterion validity. HTMT ratios of all the subscales were below 0.85, denoting good discriminant validity. The values of coefficient alpha in the three samples ranged between 0.90 and 0.93. In path analysis, correlated intrusion and hyperarousal had direct positive effects on avoidance, numbing, sleep, and irritability. Numbing and irritability mediated the indirect effects of intrusion and hyperarousal on sleep and avoidance. This result signifies that cognitive activation is the main factor driving the dynamics underlying the behavioral, emotional, and sleep symptoms of collective COVID-19 trauma. The findings support the robust validity of the Arabic IES-R, indicating it as a sound measure that can be applied to a wide range of traumatic experiences. the mechanism through which cognitive activation may affect sleep, mood, and avoidance aspects of COVID-19 trauma in our samples. This cross-sectional study is a secondary analysis based on three convenience samples collected from Saudi Arabia during the lockdown period (29 April until 19 May 2020). The first sample (N = 214) was collected from seven quarantine settings in Riyadh and Qassim. It comprised travelers returning back to Saudi Arabia, with suspected COVID-19, or mild cases. This sample is referred to herein as the quarantine sample. In Saudi Arabia, quarantine settings are hotels designated for quarantine purposes. The capacity of each setting varies from 40 to 200 rooms. They are equipped with doctors, nurses, social workers, and psychologists. Each individual is placed in a single room alone for a planned period of 14 days. The residents are observed for vital signs at least twice a day, and they receive necessary medication prescribed by the doctor on duty [30] . A sample of 1160 community-dwelling individuals was collected through invitations disseminated via WhatsApp and Twitter groups. Sample 1 comprised 168 respondents who testified having a pre-existing mental disorder diagnosed by a psychiatrist. Sample 2 comprised 992 individuals testifying an absence of mental diseases. From all respondents, including those in quarantine, data were collected through an anonymous online survey delivered through Google Forms. Individuals were included in the study if they were 18 years or older, could speak Arabic, and signed a digital informed consent. Further details are described elsewhere [6, 29] . The online questionnaire consisted of several parts. The first part assessed sociodemographic and clinical characteristics of the participants. It contained questions about gender, age, education, and having a medical diagnosis of a pre-existing mental health problem. Accordingly, participants reporting a diagnosis of a psychiatric disorder were included in the clinical sample (sample 1) while participants reporting an absence of a clinical diagnosis were included in the general public sample (sample 2). The second part consisted of the IES-R. The IES-R comprises 22 items in three subscales, which describe the major features (intrusion, avoidance, and hyperarousal) of PTSD relevant to a specific trauma-COVID-19 in the current context. An example intrusion item is "thought of it when I didn t mean to" (item 6). An example avoidance item is "tried not to think about it" (item 11). An example hyperarousal item is "was watchful or on-guard" (item 21) [16] . The internal consistency of the IES-R is good (α = 0.93) with a test-retest reliability of 0.95 [25] . We obtained this Arabic version of the IES-R (File S1) from Davey and co-workers who translated the scale into Arabic and back-translated it into English according to standards declared by the World Health Organization. They reported good reliability of the IES-R (α = 0.93) and its subscales: intrusion (α = 0.77), avoidance (α = 0.75), and hyperarousal (α = 0.86) [24] . The third part of the questionnaire consisted of the validated Arabic version of the DASS-21. This scale consists of three subscales, which measure symptoms of depression, anxiety, and stress. Each subscale consists of 7 items. Items are rated on a 4-point scale that ranges from 0 (did not apply to me at all) to 3 (applied to me very much or most of the time). The DASS-21 demonstrates good internal consistency (α = 0.88) [31] . However, it does not discriminate mental symptoms underlying the tripartite model (depression, anxiety, and stress) [31] [32] [33] . Discriminant validity tests uncovered better discrimination among the subscales of the DASS-8, a shortened version of the DASS-21, than the parent scale [28] . Therefore, we included the DASS-8 in the present analysis for criterion validity testing. The DASS-8 comprises eight items in three subscales: depression (three items, e.g., had nothing to look forward), anxiety (three items, e.g., felt close to panic), and stress (two items, e.g., found it difficult to relax). The minimum score of the DASS-8 and its subscales is 0 while their maximum scores are 24, 9, 9, and 6 , respectively [28, 29] . The reliability of the DASS-8 and its subscales ranges from excellent to very good in sample 1 (α = 0.94, 0.85, 0.89, 0.84, respectively) and sample 2 (α = 0.91, 0.79, 0.79, 0.80, respectively) [29] . A single question was used to assess perceived health status "rate your physical health status on a scale from 1 = very bad to 5 = very good". One question was used to assess participants perceived vulnerability to COVID-19 "rate your perceived vulnerability to COVID-19 on a scale from 1 = very unvenerable to 5 = very vulnerable". The study plan was approved by the Institutional Review Board of Al Qassim University (No.19-08-01). Participants who accessed the questionnaire were first introduced to a consent form confirming that the purpose of data collection was purely scientific and that participation was voluntary as it would help the researchers explore the psychological impact of the COVID-19 outbreak. The form presented information on the average time required to complete the questionnaire. It also noted that the questionnaire was anonymous and emphasized that collected personal data would not be disclosed, shared, or communicated to anyone. The dimensionality of the Arabic version of the IES-R was tested in the quarantine sample using EPA, with maximum likelihood method of extraction, varimax rotation, Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy, and Bartlett s test of sphericity. In addition, CFA (maximum likelihood with bootstrapping based on 2000 random replications) was used to examine data fit to a number of competing models in sample 1 and sample 2. Based on previous research that assessed the latent factor structure of the IES-R, we tested the theory-based three-factor structure as well as a one-factor structure, five-factor structure, and six-factor structure in addition to three bifactor structures. Modeldata fit was evaluated based on Comparative Fit Index (CFI), Tucker-Lewis Index (TLI), root mean square error of approximation (RMSEA), and standardized root mean square residual (SRMR). Acceptable fit can be achieved by CFI and TLI values above 0.90, along with RMSEA and SRMR values less than 0.08 [34] . Multigroup CFA was used to evaluate the invariance of the best fitting structure of the IES-R across groups of gender, age, and marital status (see Table 1 for categories). Four models were tested to examine whether the same number of factors are expressed in groups (configural invariance), items load equally on corresponding factors across groups (metric invariance), true mean differences do not vary as a result of constraining intercepts of the regression equations of items on the corresponding factors to equality across groups (scalar invariance), and items display uniqueness (strict invariance) [35, 36] . Sample size may affect the values of chi square (χ 2 ) index, resulting in the disqualification of fitting models, which demonstrate minor modifications. Therefore, non-invariance was evaluated based on absolute fit indices, which are less likely to be affected by sample size. Particularly, models were deemed non-invariant based on a significant χ 2 , along with ∆CFI and ∆RMSEA above 0.02 and 0.015, respectively. In CFA and multigroup CFA, suggestions indicated by modification indices were performed in order to improve model fit. Coefficient alpha, item-total correlations, and alpha if item deleted were used to assess the internal consistency of the IES-R. Spearman s r correlation between the IES-R and its subscales was conducted to determine convergent validity. Spearman s r correlation between the IES-R and criterion variables (the DASS-8 and its subscales, perceived vulnerability to COVID-19, and perceived physical health status) was used to reflect on the criterion validity of the IES-R. Discriminant validity of the IES-R was evaluated in sample 1 and sample 2 by the heterotrait-monotrait (HTMT) ratio of implied correlations associated with CFA [28] . Known-group validity of the IES-R was evaluated by Mann-Whitney U test, which was employed to compare IES-R scores between quarantined and non-quarantined participants as well as between non-quarantined healthy individuals and psychiatric patients [29, 36] . A path analysis structural equation model (SEM) was conducted to examine the relationship among factors comprising the IES-R in the three samples. Analyses were conducted in SPSS and AMOS version 24, and significance was considered at 0.05 two-tailed. As shown in Table 1 , the quarantine sample comprised more males than females. Meanwhile, the majority of the participants in sample 1 and sample 2 were females. The age of around half the participants ranged between 18 and 30 years. Most participants in all the samples had a bachelor's degree. In the quarantine sample, 7.9% (n = 17) of the respondents reported a pre-existing psychiatric disorder. As for sample 1, depression, generalized anxiety disorder (GAD), and obsessive-compulsive disorder (OCD) prevailed in 54.9%, 50%, and 20.5% of the participants, respectively. Few patients were diagnosed with bipolar disorder (6.6%), personality disorders (7.4%), eating disorders (5.7%), sleep disorders (4.1%), and psychotic disorders (2.5%). A considerable number of patients had dual diagnosis, e.g., GAD and/or sleep disorders on top of depression or OCD. More participant characteristics are reported elsewhere [6, 29] . Structure of the Arabic Version of the Impact of Event Scale-Revised (IES-R) 3.2.1. Exploratory Factor Analysis EFA using maximum likelihood with varimax rotation revealed that the items of the IES-R in the quarantine sample covered five factors with eigenvalues > 1, accounting for 62.0% of the variance. Table 2 shows that several items cross-loaded on two or more factors. The KMO test indicated that the participant-to-item ratio was proper for an EFA test. Likewise, Bartlett s test denoted appropriateness of the sample size for EFA analysis ( Table 2 ). Several competing models of the structure of the IES-R were tested in this study. Supplementary Table S1 describes the factor structure and items on each factor in every tested model. Table 3 shows that the one-factor structure of the IES-R (Model 1) expressed poor fit in both samples in terms of low CFI and TLI and high RMSEA and SRMR, along with several correlated errors. Model 2 was used to evaluate the proposed three-factor structure of the IES-R (intrusion, avoidance, and hyperarousal). This model and the bifactor structure based on this model had unsatisfactory fit, particularly in the clinical sample. Guided by the results of EFA (see the footnote of Table 2 ), we tested a five-factor structure (Model 4) including avoidance, intrusion, hyperarousal, difficulty sleeping and concentrating, and numbing. As displayed in Table 3 , this model expressed a poor fit. Modification indices revealed that several items had high cross-loadings. Therefore, we kept the five-factor structure but modified the model to allow items with cross-loadings to load only on factors to which they expressed the highest loadings (Model 5). This model has been further modified by forcing items with lower loadings on their domain-specific factors to load on more relevant factors-sleep and irritability/dysphoria appeared as distinct factors in Model 7. Table 3 . Goodness-of-fit indices for models of the Arabic version of the Impact of Event Scale-Revised (IES-R) tested by confirmatory factor analysis in psychiatric patients and healthy adults. Sample The bifactor structures examined in Model 6 and Model 8 (five and six domain-specific factors along with a general factor) expressed the best fit in sample 2, with all the items of the IES-R loading significantly on the general factor and their domain-specific factors. However, in both models, the loadings of item 20 were less than 0.2 and the loadings of items 7 and 19 were less than 0.3 (Supplementary Excel S1), indicating weak association with their domain-specific factors. Although Model 6 expressed the best acceptable fit in the clinical sample, item 21 failed to load on the numbing factor, and all the items of the intrusion factor failed to load on their specific factor. Standard errors associated with the items of the intrusion factor were considerably greater than 1 (16.1 to 95.3). In addition, SRMR was not produced due to failure of this model to properly converge. Likewise, Model 8 expressed the best fit compared with other models tested in sample 1. However, item 20 did not load significantly on its corresponding intrusion factor while the loadings of items 3, 19, and 21 on their domain-specific factors were less than 0.3 (Supplementary Excel S1), denoting that these items had limited contributions to the variance explained by the corresponding factors. The second-order factor structure (Model 9) had a fit slightly lower than that of the six-factor structure in both samples. Accordingly, the six-factor structure seems to represent the best fit in both samples ( Figure 1 ). Based on model fit indices, Model 7 was examined for measurement invariance across groups of gender, age, and marital status in both samples. Multigroup CFA showed that the six-factor structure of the IES-R holds configural, metric, and scalar invariance across different groups in both samples, i.e., this model is generally fitting similarly across men and women, young and older, as well as single and married participants. There was a tendency toward strict non-invariance across groups of age and marital status in both samples and across gender in sample 2-as noted by ΔCFI greater than 0.02. However, Based on model fit indices, Model 7 was examined for measurement invariance across groups of gender, age, and marital status in both samples. Multigroup CFA showed that the six-factor structure of the IES-R holds configural, metric, and scalar invariance across different groups in both samples, i.e., this model is generally fitting similarly across men and women, young and older, as well as single and married participants. There was a tendency toward strict non-invariance across groups of age and marital status in both samples and across gender in sample 2-as noted by ∆CFI greater than 0.02. However, ∆RMSEA was within the acceptable range (Tables 4 and 5 ). Scalar invariance expressed by this model indicates the suitability of the IES-R to portray variations in true mean differences between groups. Accordingly, Mann-Whitney U test was used to compare differences in the IES-R and the underlying six latent constructs between groups. In sample 1, there were no significant differences in the scores of the IES-R and most of its subscales between men and women, single and married, or individuals aged 30 years or below and those older than 30 years. Only women and participants aged 30 years or below expressed significantly higher levels of irritability/dysphoria than men and older participants (U = 2233.0, 2744.5; z = −2.4, −2.5; p = 0.015, 0.012, respectively). As for sample 2, the scores of the IES-R and its subscales, except for sleep disturbance, were significantly higher among women than men (all p values = 0.001). The scores of the IES-R, intrusion, hyperarousal, and irritability/dysphoria were significantly higher among single and younger participants in this sample (all p values < 0.01). Single participants also expressed significantly higher levels of sleep disturbance (p = 0.002). Values of the Mann-Whitney U test and related z scores are shown in Supplementary Excel S1. 3.3. Reliability, Convergent Validity, Normality, Criterion Validity, and Known-Group Validity of the Arabic Version of the Impact of Event Scale-Revised (IES-R) In order to identify items that may represent a source of misfit, we checked scale reliability and the range of alpha if item deleted. Reliability analysis revealed excellent internal consistency of the IES-R in the quarantine sample, sample 1, and sample 2 (α = 0.90, 0.93, and 0.92, respectively) while alpha if item deleted indicated no further increase in the reliability of the scale following any item removal (range = 0.892 to 0.902, 0.917 to 0.923, and 0.909 to 0.915 in both samples, respectively). Table 6 shows good internal consistency of the factors comprising Model 7, albeit the reliability of the numbing factor was fair in the quarantine sample and acceptable in the other samples. All the six factors had strong positive correlations with the total scores of the IES-R in the three samples (r ranges between 0.653 and 0.867). Shapiro-Wilk W test shows that the IES-R and its underlying six factors displayed a non-normal distribution, with all p values < 0.001. As hypothesized, strong positive correlations were expressed among the scores of the IES-R and the scores of the DASS-8 and its subscales in all the samples (r ranges between 0.176 and 0.716, all p values < 0.01). Perceived health status was negatively correlated with the IES-R and its subscales. Meanwhile, the IES-R scores were positively correlated with perceived vulnerability to COVID-19 (Table 6 ). These results reflect sound criterion validity of the IES-R in all the samples. As shown in Table 7 , Mann-Whitney U test revealed significantly higher levels of the IES-R, avoidance, hyperarousal, sleep disturbance, and irritability/dysphoria among quarantined than community-dwelling participants (p values < 0.05). The scores of the IES-R and all its six factors were significantly higher among psychiatric patients compared with those without a psychiatric diagnosis (all p values < 0.01), which supports known-group validity of the scale. Table 7 . Descriptive statistics and known-group validity of the Arabic version of the Impact of Event Scale-Revised (IES-R) and the factors it comprises among quarantined, psychiatric, and healthy samples. In the tested models, all non-significant paths were trimmed. As shown in Supplementary Table S2 , all path analysis models displayed excellent fit on all indices. In the quarantine sample, the path model explained 38%, 44%, 24%, and 34% of the variances in irritability, sleep disturbance, numbing, and avoidance. Intrusion only had significant direct effects on sleep disturbance and numbing (p = 0.048, 0.043); its indirect effects on avoidance and sleep disturbance were non-significant (p values > 0.05). The direct effects expressed by hyperarousal and numbing were significant at the level of 0.001 (Figure 2a) . Numbing mediated the indirect effects of hyperarousal on avoidance and sleep disturbance (β = 0.109, 0.056; 95% CI: 0.60-0.172, 0.018-0.103; p = 0.001, 0.003). In the healthy community sample, the path model explained 38%, 42%, 34%, and 45% of the variances in irritability, sleep disturbance, numbing, and avoidance. All direct effects were significant at the level of 0.001 (Figure 2c) . Numbing mediated the indirect effects of intrusion and hyperarousal on avoidance (β = 0.163, 0.101; 95% CI: 0.132-0.197, 0.069-0.132; p values = 0.001) and on irritability (β = 0.065, 0.040; 95% CI: 0.041-0.094, 0.025-0.061; p values = 0.001). Irritability mediated the indirect effects of intrusion, hyperarousal, and numbing on sleep disturbance (β = 0.041, 0.064, 0.027; 95% CI: 0.024-0.064, 0.038-0.097, 0.014-0.046; p values = 0.001). The Arabic version of the IES-R has been previously evaluated only through EFA among 40 Arab refugees in Australia. The current study examined the factor structure of the Arabic IES-R (using EFA and CFA), along with its measurement invariance, convergent validity, normality, criterion validity, known-group validity, and discriminant validity. Therefore, the findings complement existing knowledge by reporting on various psy- In the psychiatric patient sample, the path model explained 40%, 47%, 29%, and 49% of the variances in irritability, sleep disturbance, numbing, and avoidance. All direct effects were significant at the level of 0.001 (Figure 2b) . Irritability mediated the indirect effects of intrusion and hyperarousal on sleep disturbance (β = 0.093, 0.120; 95% CI: 0.046-0.160, 0.056-0.214; p values = 0.001). Numbing mediated the indirect effects of intrusion and hyperarousal on avoidance (β = 0.084, 0.067; 95% CI: 0.30-0.173, 0.025-0.132; p = 0.004, 0.010). In the healthy community sample, the path model explained 38%, 42%, 34%, and 45% of the variances in irritability, sleep disturbance, numbing, and avoidance. All direct effects were significant at the level of 0.001 (Figure 2c The Arabic version of the IES-R has been previously evaluated only through EFA among 40 Arab refugees in Australia. The current study examined the factor structure of the Arabic IES-R (using EFA and CFA), along with its measurement invariance, convergent validity, normality, criterion validity, known-group validity, and discriminant validity. Therefore, the findings complement existing knowledge by reporting on various psychometric properties of the IES-R in three samples (psychiatric patients, healthy adults, and quarantined individuals) from an Arab country within the context of a collective traumatic event (the COVID-19 outbreak and associated lockdown). This study could not replicate the theory-based three-factor structure of the IES-R, at least among psychiatric patients. As shown in Table 2 , most items had dual or triple loadings greater than 0.3 on more than one factor indicating absence of a well-defined structure of the scale. Several competing models tested in CFA revealed an unsatisfactory fit in the clinical sample. The three-factor structure of the IES-R and a bifactor structure based on that model expressed an acceptable fit in sample 2. However, the best fit in both sample 1 and sample 2 was expressed by a six-factor structure (Model 7) comprising avoidance, intrusion, hyperarousal, numbing, sleep disturbance, and irritability/dysphoria. The six-factor structure is superior to other models tested in this study because items have moderate to strong loadings on their domain-specific factors (Figure 1 ), and they do not cross-load, signifying fulfillment of the assumption of local independence. Despite the superior fit of the bifactor structure of this model in both samples, some items had low loadings on their domain-specific factors, discouraging the use of the bifactor model in subsequent analysis. Our findings are consistent with many previous studies, which reported a deviation of the dimensionality of the IES-R from the theory-based three-factor structure [16, 20, 23, 25, 26] . The literature shows a considerable debate on the dimensional structure of the IES-R. Until the current moment, there has been less consensus among trauma scientists on the best structure of symptom clusters involved in the diagnosis of PTSD [16, 20, 25, 26] . In this respect, investigations of PTSD criteria, as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV; American Psychiatric Association, 1994), among 1218 women exposed to varying levels of sexual harassment at the workplace denote failure of the intrusion, avoidance, and hyperarousal structure to depict the full picture of the disorder among these women. Alternatively, the authors suggested that PTSD is suitably described within the context of four factors: re-experiencing, effortful avoidance, emotional numbing, and hyperarousal [37] . In the same way, Baschnagel and colleagues evaluated PTSD among western New York undergraduate students one and three months after the 11 September 2001 terrorist attacks. They reported poor fit of the intrusion, avoidance/numbing, and hyperarousal structure of PTSD. Instead, they reported over-time stability of a four-factor model comprising intrusion, avoidance, dysphoria, and hyperarousal. Dysphoria comprised symptoms from hyperarousal and numbing clusters [38] . Subsequent investigations failed to produce a good fit for four-factor structures of the IES-R, which comprised standalone factors of numbing [23, 25] or dysphoria [25] . However, best fits were obtained from five-factor models including intrusion, avoidance, hyperarousal, and sleep problems in addition to numbing [25, 26] or dysphoria [25] . On the other hand, sleep-related symptoms emerged as an independent factor in investigations involving survivors of a destructive earthquake [20] , fire fighters and students [23] , as well as survivors of war [26] . A previous preliminary evaluation of the Arabic version of the IES-R also included sleep as a separate construct [24] . However, the sleep construct in our samples comprised only item 2 and item 15. On the other hand, the loadings of item 20 "had dreams about it" on the sleep factor were considerably low while the loadings of this item on the intrusion factor were above 0.4 in both samples. Having a closer look at the content of this item, dreams may be considered a form of unconscious intrusion. Indeed, the literature portrays strong links between cognitive symptoms, sleep problems, and mood dysregulation [13, 39] . In our study, irritability, numbness, and sleep were distinct factors, albeit associated with one another. Although irritability and sleep comprised only two items, their internal consistency, item loadings, and item-total correlations were all high (Table 6, Figure 1 ), supporting these experiences as vivid aspects of PTSD. Collective research suggests that the DSM-IV does not address all the psychological symptoms of PTSD [40] . Meanwhile, a huge number of models evaluating DSM-IV criteria of PTSD report numerous factors, with almost all factors comprising only two symptoms, and high inter-factor correlations are the norm [41] . The distinction between irritability and numbness can be understood within the different contexts of trauma-related emotional responses. General emotional reactions associated with traumatic events mostly comprise anger, fear, sadness, and shame. However, some individuals may be unable to identify their feelings, or they associate strong feelings with past trauma and get overwhelmed with thoughts that expressing negative feelings is dangerous or may create more severe emotions (e.g., a sense of "being out of control/losing it/or going crazy"). Others may express numbness or lack of emotions as they unconsciously deny their trauma-related feelings [40] . Noteworthily, the fit of all tested models was improved by correlating several error terms. However, the fit of the structure expressed by Model 7 (the six-factor structure) in the absence of error correlations was the closest to acceptable fit in sample 1 (χ 2 (194) = 376.248, CFI = 0.891, TLI = 0.870, RMSEA = 0.075, SRMR = 0.0630) and sample 2 (χ 2 (194) = 1070.016, CFI = 0.904, TLI = 0.886, RMSEA = 0.068, SRMR = 0.0631). In the meantime, correlated error terms in Model 7 were minimal, denoting a lower chance for items from different factors to flag something other than their respective latent variables. In sample 1, the fit of Model 7 was improved by correlating the error term of item 5 "avoided letting myself get upset" with those of items 4 "was irritable or angry" and 6 "thought of it when I didn t mean to". Item 16 "waves of strong feelings" was also correlated with the error of item 19 "reminders of it caused physical reactions e.g., sweating, dyspnea". In sample 2, the error term of item 5 was correlated with the errors of item 1 "reminder brought back feelings", item 3 "making me think about it", items 4, 6, and 9 "images popped into my mind". Multicollinearity generally suggests the presence of extra latent structures. However, the interactions taking place among these variables may be triggered by method effects, i.e., the sequential appearance of these symptoms on the questionnaire. Alternatively, the wording of these variables denotes that cognitive activation may be evoked by intrusive thoughts about COVID-19 (items 6 and 19) . Such cognitive activation may stimulate uncomfortable emotional (items 4 and 16) and physical reactions (item 19). Accordingly, individuals employ avoidance to escape negative emotions and uncomfortable sensory symptoms associated with intrusive thoughts (item 5) or reminders (item 19) . Path analysis investigating the relationships among the six factors comprising the Arabic version of the IES-R conforms with this logic. In consistence with an existing Italian study [7] , intrusion was associated with hyperarousal in all the samples (Figure 2) , and both factors directly and indirectly predicted avoidance, irritability, and sleep disturbance. Their indirect effects were mediated by irritability and numbing. The effects of intrusion on other dimensions of the IES-R were most pronounced in the healthy and clinical samples (who were community residents) than in the quarantine sample (Table 7 and Figure 2 ). This result draws support from previous investigations showing protective effects of being in isolation against COVID-19-related trauma and distress [6] . The literature refers to the COVID-19 pandemic as a collective trauma, with people experiencing traumatizing information (e.g., about job loss, food shortage, rising prices, etc.) and pictures/videos of health professionals in their quarantine uniform dragging COVID-19 victims on trollies (e.g., on the news and social media) on a daily basis [4] . Although some individuals may be overwhelmed by the trauma, others may get desensitized over time [5] . The six-factor structure was obtained in psychiatric patients and healthy adults. This finding is consistent with those of Gargurevich and colleagues indicating no difference in the overall structure of the IES-R between fire survivors and university students [23] . As shown in Figure 1 , most item loadings were a little bit greater in the clinical sample than in the general public sample. The scores of all the six factors were also greater in the clinical sample (Table 7 ). These results denote that innate stress endorsed by psychiatric patients may increase the intensity of their experience of PTSD [20] . Analysis of measurement invariance revealed that the six-factor structure of the IES-R was invariant at the configural, metric, and scalar levels across groups of gender, age, and marital status. This result is similar to that reported by Wang et al. [20] who found that a four-factor structure model holds invariance across men and women. However, in their study, item intercepts based on magnitudes of factor loadings across samples were significantly non-equivalent, denoting a degree of scalar non-invariance [20] . Scalar invariance of the IES-R expressed in the present study allowed us to compare IES levels between groups. Women and young participants expressed considerably higher levels of trauma than men and older participants in all the samples (Table 7 ). In accordance, comparisons involving the parents of children diagnosed with epilepsy reflect a higher prevalence of PTSD among women. Men and women experiencing PTSD are reported to exhibit obvious differences in symptom clusters except for avoidance, with women being high on cognitive and somatic symptoms [42] . Irritability, mood dysregulation, and sleep disturbance are associated with continuous activation of the sympathetic nervous system and persistent dysregulation of the hypothalamic-pituitary-adrenal axis [43] . Research reports varying levels of corticotropin-releasing factor level and their association with PTSD symptoms across men and women [18] . Therefore, the differences between men and women in our samples as well as in other studies reflect higher susceptibility of females to react more excessively to traumatic events than their male counterparts. All the items of the IES-R had strong significant positive correlations with the total scores of the IES-R and their domain-specific factors. Values of alpha if item deleted indicated no further increase in scale reliability following any item deletion. Item-total correlations as well as correlations of the factors with the total score of the scale were high, denoting adequate convergent validity of the IES-R, with no need to remove any item from the scale/subscales. External validity of the IES-R was supported by its positive correlation with the DASS-8, its subscales (depression, anxiety, and stress), as well as perceived vulnerability to COVID-19. Its negative correlation with perceived health status is consistent with the literature reporting higher COVID-19 trauma among people with poor physical health [6] . The IES-R scores were significantly higher among quarantined individuals and psychiatric patients compared with non-quarantined individuals and the general public, which lends further support to its known-group validity. The subscales of the IES-R were not overlapping with one another, as indicated by HTMT ratios below 0.85 in sample 1 and sample 2 (Supplementary Excel S2). This result supports the discriminant validity of the scale as well as usability of the six subscales to capture the distinct manifestations of trauma. To our knowledge, this study is the first to investigate the psychometric qualities of the Arabic IES-R in three relatively large samples. Including psychiatric patients and the general public permitted us to evaluate if co-morbidity might affect the structure of the Arabic IES-R. Moreover, sophisticated tests were included such as EFA, CFA, measurement invariance, and HTMT. Thus, our study counteracts obstacle endorsed by former investigations of the Arabic IES-R, such as the use of a small sample size and limited methods of analysis [24] . The findings emphasize that the items of the IES-R cover more than three factors-sleep problems, numbing, and irritability/dysphoria seem to be important aspects of PTSD experiences. Despite these strengths, the results should be interpreted with caution because the study has a number of limitations. Using an online survey as a method to recruit respondents may entail selection bias in terms of including more young people who have some affinity to technology and certain economic background (e.g., they afford a mobile device). Older adults are more vulnerable to severe COVID-19, and their emotional reaction to the pandemic may differ from younger groups. However, we could not test sub-group differences in trauma because those above the age of 50 were less presented (6.1, 9.5, and 14.0% of the quarantine, psychiatric, and healthy samples, respectively (see Supplementary Excel 1 for all age categories)). As the survey was disseminated through social media such as Twitter and WhatsApp, individuals taking part in the psychiatric sample may express lower severity than those who decided not to take part in the survey. The cohorts included were highly heterogenous. For example, females represented a majority in all samples. As noted above, gender may considerably contribute to differences in PTSD symptoms. Data were collected during a restricted period of time at the beginning of the COVID-19 pandemic (29 April-19 May 2020). The number of all confirmed cases in Saudi Arabia did not exceed 1000 at that time. However, the number of cases and disease fatalities have increased given that the pandemic is still ongoing. Therefore, the current levels of psychological distress and trauma associated with the outbreak may be greater than those reported in the present study. In addition, the IES-R was evaluated within the COVID-19 context and extending its functionality to other traumas such as violence, burn, and route traffic accidents may be necessary. More robust methods such as item response theory may be used in future studies to explore the definite relationships among the items of the IES-R and the latent constructs (e.g., item difficulty and discrimination). The Arabic IES-R is best described by a six-factor structure comprising avoidance, intrusion, numbing, hyperarousal, sleep problems, and irritability/dysphoria. The scales are quite discrete, and their scores are higher among psychiatric patients, supporting the known-group validity of the IES-R. The scale expresses excellent internal consistency and strong convergent and criterion validity both in psychiatric patients and in the general public. It operates evenly across groups of gender, age, and marital status, which indicates its appropriateness as a measure of psychological trauma among different groups. Supplementary Materials: The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/jpm12050681/s1, Table S1 : Factors and corresponding items on every model; Table S2 : Goodness-of-fit indices for structural equation models examining interactions among factors comprising the Arabic version of the Impact of Event Scale-Revised (IES-R); Supplementary Excel S1: extra results of of CFA, known-group validity, etc., which are referred to but not reported in the manuscript; Supplementary Excel S2: HTMT ratios of the factors comprising the IES-R in sample 1 and sample 2; File S1: The Arabic version of the Impact of Event Scale-Revised (IES-R)-reproduced with permission from Davey et al. [24] . 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The dataset used to produce the current study can be found in Mendeley repository at: https://data.mendeley.com/datasets/8k3vmfxpd3/draft?a=67415321-61f7-4920-bd2a-749b365ff6fb (accessed on 18 March 2022). The authors declare no conflict of interest.