key: cord-0825013-zv3s7cjq authors: Thirunavukarasu, Arun James title: Evaluating the mainstream impact of ophthalmological research with Google Trends date: 2020-11-01 journal: Eye (Lond) DOI: 10.1038/s41433-020-01257-4 sha: ca3b2a1573089bf98902669fb2f1ca570c7ddeae doc_id: 825013 cord_uid: zv3s7cjq nan Google interest in ophthalmological conditions was greatest between 2004 and 2005, falling to a minimum around 2011 with a subsequent rise to the present day interrupted by a sharp drop in March 2020 ( Fig. 1) , likely due to disproportionate interest in the Covid-19 pandemic. In contrast, PubMed publications tended to grow steadily, with a drop in 2020 ( Fig. 1 ), attributable to both the pandemic and lack of four months' research relative to other years. A scatter plot relating the two variables ( Fig. 2 ) indicated weak positive correlation overall, with most points lying outside the 95% confidence intervals of the best-fit trend-line. No correlation was apparent within search terms. Correlation coefficients agreed with these deductions, with overall positive correlation (τ = 0.620, p = 1.35E−26) and no significant correlations (p > 0.05) within search terms. The overall correlation between Google interest and PubMed publications indicates concordance between the interests of the scientific community and general public. However, lack of correlation within conditions suggests that ophthalmological research has little direct effect on laypeople's interests, which may instead be closer related to the prevalence of the respective conditions. Correlation could also be masked by the lack of normalisation of PubMed data: ophthalmology may not have kept up with inflation observed across the scientific literature over time. Further investigations could explore the effect on Google interest of high impact publications, or publication-inspired news pieces. Similar ophthalmological event analyses have previously been conducted, evaluating the effect of public health campaigns [3] , conjunctivitis epidemics [4] and Bono developing glaucoma [5] . Google trends as a surrogate marker of public awareness of diabetic retinopathy The use of google trends in health care research: a systematic review Exploring the impact of public health campaigns for glaucoma and macular degeneration utilising Google Trends data in a New Zealand setting Google searches and detection of conjunctivitis epidemics worldwide Still haven't found what i'm looking for… Bono, google and glaucoma awareness Conflict of interest The author declares no conflict of interest.Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.