key: cord-0821230-z2z4gte2 authors: Veraldi, Stefano; Angileri, Luisa; Barbareschi, Mauro title: Seborrheic dermatitis and masks date: 2020-08-13 journal: J Cosmet Dermatol DOI: 10.1111/jocd.13669 sha: 12f8ee35b9f5436574124fcc10e8d8c55fa3e1b0 doc_id: 821230 cord_uid: z2z4gte2 In Milan, Italy, after the end of the lockdown period (March and April 2020), we observed several patients with seborrheic dermatitis (SD) who showed a more or less important worsening of their disease. All patients used anti‐coronavirus‐19 (COVID‐19) face mask for many hours per day. According to the clinical point of view, the worsening was characterized by increased erythema and desquamation as well as itching worsened. In the last few weeks, some articles have been published on cases of dermatitis of the face associated with the use of anti‐COVID‐19 masks. Some authors hypothesized that this condition is due to high temperature of the face covered by the mask, that induces an increased sebum excretion rate. In our patients with SD, it is possible that high temperature of the face induces abnormalities of microbiota (proliferation of Malassezia spp.?) and permeability of skin barrier, and increases sweating with irritant action and worsening of itching. view, the worsening was characterized by increased erythema and desquamation as well as itching worsened. In the last few weeks, some articles have been published on cases of dermatitis of the face associated with the use of anti-COVID-19 masks. Some authors hypothesized that this condition is due to high temperature of the face covered by the mask, that induces an increased sebum excretion rate. In our patients with SD, it is possible that high temperature of the face induces abnormalities of microbiota (proliferation of Malassezia spp.?) and permeability of skin barrier, and increases sweating with irritant action and worsening of itching. Dear Editor, In Milan, Italy, after the end of the lockdown period (March and April 2020), we observed several patients with seborrheic dermatitis (SD) who showed a more or less important worsening of their disease. In a group of 43 patients with SD who Accepted Article had been visited from December 2019 to February 2020, a worsening in 20 of them (46.5%) was seen. They were 15 males (75%) and 5 females (25%), with an age ranging from 23 to 48 years (mean age: 36.7 years). All patients used anticoronavirus-19 (COVID-19) face mask for 6 to 10 hours per day; 7 out of 20 patients (35%) were physicians, obstetricians or nurses. According to the clinical point of view, the worsening was characterized by increased erythema and desquamation ( Figures 1 and 2) . Fourteen out of 20 patients (70%) stated that also itching worsened. In the last few weeks, some articles have been published on cases of dermatitis of the face associated with the use of anti-COVID-19 masks. [1] [2] [3] [4] [5] In a Chinese study, it was observed that 49% of subjects reported skin reactions on the face related to mask. Itch (14.9% of patients), erythema (12.6%) and dryness (11.6%) were the most frequent manifestations. Furthermore, 43.6% of patients with acne, 100% of patients with rosacea and 37.5% of patients with SD reported exacerbation of their diseases. 1 A Polish study demonstrated that itching associated with the use of face mask was present in 19.6% of subjects. In particular, subjects with atopic dermatitis, SD and acne were at significantly higher risk of itching development. Furthermore, subjects who wore masks for many hours per day reported itching more frequently. 2 A case of occupational allergic contact dermatitis caused by formaldehyde and 2-bromo-2-nitropropane-1,3-diol (bronopol) contained in a polypropylene surgical mask was published. 3 In another Chinese study, it was observed a significant increased flare of acne in individuals with long time mask wearing (>4 hours per day over two months). The authors hypothesized that this condition is due to high temperature of the face covered by the mask, that induces an increased sebum excretion rate: the latter increases by 10% for each 1°C rise. 4 In our patients with SD, it is possible that high temperature of the face induces Skin reactions of N95 masks and medial masks among health-care personnel: A self-report questionnaire survey in China. Contact Dermatitis Face mask-induced itch: a self-questionnaire study of 2.315 responders during the COVID-19 pandemic Surgical mask dermatitis caused by formaldehyde (releasers) during the COVID-19 pandemic Increased flare of acne caused by long-time mask This article is protected by copyright. All rights reserved abnormalities of microbiota (proliferation of Malassezia spp.?) and permeability of skin barrier, and increases sweating with irritant action and worsening of itching. The authors declare there are no conflicts of interest -financial or otherwiserelated to the material presented herein. Informed consent and permission for publication of medical images was taken from the patient.