key: cord-0802357-6gxglcm4
authors: Lombardi, Carlo; Roca, Elena; Bigni, Barbara; Cottini, Marcello; Passalacqua, Giovanni
title: Clinical course and outcomes in patients with asthma hospitalized for SARS-CoV-2 pneumonia:a single-center, retrospective study.
date: 2020-08-01
journal: Ann Allergy Asthma Immunol
DOI: 10.1016/j.anai.2020.07.029
sha: 2bd337dd16d8dcba8d0a1437b9b761d642bf8971
doc_id: 802357
cord_uid: 6gxglcm4

nan

hospitalized for SARS-CoV-2 pneumonia : a single-center, retrospective study. (1) Asthma Center & COVID Unit,Departmental Unit of Pneumology & Allergology, Istituto Ospedaliero "Fondazione Poliambulanza", Brescia (Italy);

(2) COVID Unit, Istituto Ospedaliero "Fondazione Poliambulanza", Brescia (Italy);

(3) Allergy and Pneumology Outpatient Clinic, Bergamo, Italy;

(4) Allergy Authors Contribution: 1) Carlo Lombardi : he made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data; he drafted the article and reviewed it critically for important intellectual content; 2) Elena Roca: drafted the article and reviewed it critically for important intellectual content; 3) Barbara Bigni: drafted the article and reviewed it critically for important intellectual content; 4) Marcello Cottini : he made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data; he drafted the article and reviewed it critically for important intellectual content; 5) Giovanni Passalacqua: he given final approval of the version to be published. SARS-CoV-2 pneumonia is a newly recognised illness that has spread rapidly from Wuhan to other 1 provinces in China and around the World. Italy was one of the most affected countries. From 2 february 2020, Lombardy (northern Italy), was the most affected region by the COVID-19 3 infection, with a total number of positive cases equal to 93.990 and a total number of deaths of 4 16.302 (data as at 2 July 2020). In particular, Brescia was one of the provinces of Lombardy most 5 affected by the pandemic. The data on the clinical characteristics and outcomes of asthmatics with SARS-CoV-2 infection are 7 scarce, but are of paramount importance to evaluate the relationship between COVID-19 and 8 asthma. Given the characteristics of the virus, one would expect to observe an increased 9 prevalence of asthma and wheezing exacerbations in COVID-19 patients with allergy and asthma 10 comorbidity, a typical consequence in case of a viral respiratory infection (1). In this single-centre, 11 observational study, we investigated asthmatic patients with confirmed SARS-CoV-2 pneumonia 12 who were admitted to our hospital (Fondazione Poliambulanza Istituto Ospedaliero, Brescia,Italy), 13 which is one of designated hospital to treat patients with SARS-CoV-2 pneumonia. We 14 retrospectively evaluated the data of asthmatic patients from february 20, 2020, to april 20, 2020, 15 who had been diagnosed with SARS-CoV-2 pneumonia. Asthma was identified as diagnosed by 16 physicians and by the standard criterion used for several real-life studies, and in most of our cases 17 the diagnosis was supported by previous historical standard spirometry with reversibility test with 

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