key: cord-0799634-3ef931d4
authors: Baeck, Marie; Herman, Anne; Peeters, Caroline; Marot, Liliane; Hermans, Cedric
title: Are chilblains a skin expression of COVID‐19 microangiopathy?
date: 2020-07-13
journal: J Thromb Haemost
DOI: 10.1111/jth.15008
sha: 5e1fe63b036422e9c9a746cde0d9a6a767bc29e5
doc_id: 799634
cord_uid: 3ef931d4

The unexpected outbreak of chilblains during the current coronavirus disease 2019 (COVID‐19) pandemic has been causally linked to severe acute respiratory syndrome coronavirus 2 (SARSCoV‐2) infection (1). The pathophysiology of these chilblains observed in otherwise healthy patients is widely discussed.

pandemic has been causally linked to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (1) . The pathophysiology of these chilblains observed in otherwise healthy patients is widely discussed.

This article is protected by copyright. All rights reserved Accepted Article pandemic, also suggest that their pathological features are similar to those of idiopathic and autoimmune-associated chilblains, including vascular microthrombosis (7) .

Altogether, these findings confirm that chilblains lesions in healthy patients have no relationship with the microthrombotic vasculopathy, mainly triggered by endothelial damage (probably due to direct viral effect and perivascular inflammation), observed in critical COVID-19.

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covid toes"): histologic, immunofluorescence and immunohistochemical study of 17 cases

This article is protected by copyright. All rights reserved