key: cord-0797770-hd0t6w35 authors: Binois, Raphaëlle; Colin, Mathilda; Rzepecki, Vincent; Prazuck, Thierry; Esteve, Eric; Hocqueloux, Laurent title: A case of erythema multiforme major with multiple mucosal involvements in COVID‐19 infection date: 2020-11-23 journal: Int J Dermatol DOI: 10.1111/ijd.15158 sha: d883b1cbd9294f5a293bbe5550a6a1c4acdd4e25 doc_id: 797770 cord_uid: hd0t6w35 nan Herein, we report on a case of severe and pure mucous damages in a COVID-19-positive inpatient. This case brings additional data implementing the knowledge on the dermatological signs during COVID-19. A 57-year-old man with no medical history had first complained of cough, headache, myalgia, and fever for 3 days, before all symptoms resolved spontaneously. Five days later, he presented to the emergency department with painful gingivostomatitis, fever (39°C), ageusia, and anosmia and was hospitalized as a result of complete inability to eat or drink. Physical examination found bilateral ulcers of the mouth (a and b) and glans (c), erythematous conjunctivitis (d), but no other lesion on the whole tegument: these findings were consistent with erythema multiforme major (Fig. 1) . Biologically, there was a marked inflammatory syndrome (CRP = 237 mg/l, elevated ferritinemia = 20 times normal) associated with hepatic cytolysis A novel coronavirus from patients with pneumonia in China Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients Cutaneous manifestations in COVID-19: a first perspective Atypical erythema multiforme palmar plaques lesions due to Sars-Cov-2 Mucosal involvement in a COVID-19-positive patient: A case report