key: cord-0795259-xgvowqw2
authors: Sueta, Daisuke; Kaikita, Koichi; Matsushita, Kenichi; Tsujita, Kenichi
title: eThrombosis: A new risk factor for venous thromboembolism in the pandemic era
date: 2020-11-10
journal: Res Pract Thromb Haemost
DOI: 10.1002/rth2.12447
sha: 5fe42def3b66f9b9732476de1a49207564c9b02f
doc_id: 795259
cord_uid: xgvowqw2

nan

In this pandemic era, we read with great interest the article in which Beasley et al 1 advocated the concept of "eThrombosis" in 2003.

Beasley et al reported a case of acute pulmonary thromboembolism with syncope in a 32-year-old man sitting in front of a computer for 18 hours. We strongly agree with their opinion that it may be possible to reduce the potential considerable burden of eThrombosis. The basic pathophysiology of eThrombosis is immobility, which corresponds to the stagnation of blood flow in Virchow's triad by prolonged sitting. There have been several case reports on the association between immobility associated with prolonged television watching and pulmonary embolism. 2,3 A later study revealed that the multivariable hazard ratio for mortality from pulmonary embolism according to hours spent watching television was 2.5 (>5 hours per day spent watching television). 4 Thus, television watching is recognized as a risk factor for venous thromboembolism (VTE). 5 The results of this previous study are consistent with the Nurses' Health Study data, in which show a close association between time spent sitting at home and the incidence of pulmonary thromboembolism. 6 Other similar times in history have seen increased rates of pulmonary embolism due to immobilization. One such case was a subway shelter during the 1940 London air raid. At this time, due to the lack of air-raid shelters in London, the narrow premises of the subway station became a spontaneous shelter, and the evacuees slept in a narrow subway platform (Figure 1 F I G U R E 1 Changes in the causes of pulmonary embolism due to immobility "Shelter in war" "Long flight"

"Night in vehicle" during disaster "eThrombosis" at pandemic

eThrombosis: the 21st century variant of venous thromboembolism associated with immobility

Watching television and pulmonary embolism

A case report on VT from TV: DVT and PE from prolonged television watching

Watching television and risk of mortality from pulmonary embolism among Japanese men and women: the JACC study

TV viewing and incident venous thromboembolism: the Atherosclerotic Risk in Communities Study

Physical inactivity and idiopathic pulmonary embolism in women: prospective study

Shelter deaths from pulmonary embolism

Pulmonary thromboembolism after travel

Travel-related venous thrombosis: results from a large population-based case control study (MEGA study)

Clinical features of patients with acute aortic dissection after an earthquake: experience from the Kumamoto earthquake 2016

Venous thromboembolism caused by spending a night in a vehicle after an earthquake

Risk factors and prevalence of deep vein thrombosis after the 2016 Kumamoto earthquakes

Functional impairment and risk of venous thrombosis in older adults

Pulmonary embolism in patients with COVID-19: awareness of an increased prevalence