key: cord-0791843-bx073k7n
authors: Dienstmann, Guilherme; Comar, Samuel Ricardo; Souza, Matheus Leite Ramos de; Ruaro, Graziela; Leite, Luiz Arthur Calheiros
title: Critical blue-green inclusions in neutrophil and monocyte cytoplasm in a healthy patient affected by COVID-19
date: 2020-07-24
journal: Hematol Transfus Cell Ther
DOI: 10.1016/j.htct.2020.06.008
sha: 38b8b007f543afdd540196325351d902d77a6b1b
doc_id: 791843
cord_uid: bx073k7n

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are also known as "crystals of death", since most patients (65%) progress quickly to death after their microscopic finding (92% within 72 h). Such inclusions have a high lipid content, which in association with their color and acidic nature, leads us to believe they are deposits of lipofuscin, which represents products of lysosomal degradation of necrotic liver cells that are phagocytized by neutrophils and monocytes (Figures 1 and 2 

The authors declare no conflicts of interest.

Q4 r e f e r e n c e s

Clinical significance of blue-green neutrophil and monocyte cytoplasmic inclusions in SARS-CoV-2 positive critically ill patients

Significance of green granules in neutrophils and monocytes

Green inclusions in neutrophils: a critical finding that must be reported