key: cord-0781426-ljle4vq3
authors: Morioka, Shinichiro; Nakamura, Keiji; Iida, Shun; Kutsuna, Satoshi; Kinoshita, Noriko; Suzuki, Tetsuya; Suzuki, Tadaki; Yamamoto, Kei; Hayakawa, Kayoko; Saito, Sho; Ohmagari, Norio
title: Possibility of transmission of severe acute respiratory syndrome coronavirus 2 in a tertiary care hospital setting: A case study
date: 2020-07-30
journal: Infection prevention in practice
DOI: 10.1016/j.infpip.2020.100079
sha: 74b0476a0ec3dd059fcd3b1533da43d386c8e2f5
doc_id: 781426
cord_uid: ljle4vq3

Summary This report aimed to investigate transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a hospital setting. A 63-year-old man with pneumonia and an asymptomatic 70-year-old man were admitted to a tertiary hospital with SARS-CoV-2 infection. Both men were accompanied by their wives, who stayed with their husbands during their hospitalisation. The wives of Patient 1 and Patient 2 tested positive and negative for SARS-CoV-2, respectively. Of the environmental samples tested, 1/21 and 0/25 from the rooms of Patient 1 and Patient 2, respectively, tested positive for SARS-CoV-2. Route of transmission from Patient 1 to his wife was unclear.

ventilation. He was admitted to a general ward of our hospital due to SARS-CoV-2 63 pneumonia on Day 7, and was intubated on Day 10 from diagnosis. He had been staying in a 64 single room in our hospital ( Figure 1A) , and used the toilet by himself before intubation. His 65 65-year old wife, who did not have any symptoms and was negative for SARS-CoV-2 before 66 admission, refused to stay apart from her husband. Thus, she stayed with Patient 1 in a single 67 room during the day, and stayed alone in the room next door at night. The healthcare providers advised her to wear a mask at all times and to wash her hands frequently, and did 69 not allow her to provide any direct patient care. She developed mild cough on Day 12 from 70 her husband's diagnosis, and was tested for SARS-CoV-2 on Day 13. 

Coronavirus Infections-More Than Just the Common 199

of Novel Coronavirus-Infected Pneumonia

Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. 208 JAMA 2020

Human-to-Human Transmission of a Novel Coronavirus in Vietnam

Outbreak of 2019 Novel Coronavirus (2019-nCoV

Extensive Viable Middle 215

East Respiratory Syndrome (MERS) Coronavirus Contamination in Air and Surrounding 216 Environment in MERS Isolation Wards

Virus 219 shedding and environmental deposition of novel A (H1N1) pandemic influenza virus: interim 220 findings

Environmental, and Personal Protective Equipment Contamination by Severe Acute 223

Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient

Evidence of airborne 226 transmission of the severe acute respiratory syndrome virus

Formal analysis, Data Curation, Writing -Original Draft, Project administration

Writing -Review & Editing, Funding acquisition. Norio Ohmagari: Supervision