key: cord-0776764-pb0hmwws
authors: Jie Chee, Ying; Jia Huey Ng, Shereen; Yeoh, Ester
title: Reply to comments on Letter to the Editor - Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus
date: 2020-07-03
journal: Diabetes Res Clin Pract
DOI: 10.1016/j.diabres.2020.108305
sha: 0671db9c60c08901be4a272cc4be8e6cb46d674b
doc_id: 776764
cord_uid: pb0hmwws

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1

Ying Jie Chee, MBBS, MRCP 1 The authors do not have any financial associations or conflicts of interests to disclose.

Thank you for your interest in our Letter to the Editor as well as your comments regarding the reference range for pH in the arterial blood gas result presented in table 1 of our letter.

Diabetic ketoacidosis (DKA) is characterized by metabolic acidosis with significant ketonemia or ketonuria in the presence of hyperglycemia. An arterial or venous pH of 7.30 and below is generally accepted as one of the diagnostic criteria 1, 2 . This patient had an arterial pH 7.28, serum bicarbonate 12 mmol/L, serum ketones 6.4 mmol/L, anion gap 30 and venous glucose 39.7 mmol/L, thereby fulfilling the diagnosis of mild to moderate DKA. We acknowledge a typographical error in the reference range for pH but this should not detract us from the diagnosis of diabetic ketoacidosis in this patient.

In addition, we also thank the authors for pointing out that pH is a logarithmic scale and should not have a unit attached.

Please find the corrected version of our table. We apologize for the errors and the inconvenience caused. 

Hyperglycemic crises in adult patients with diabetes

Joint British Diabetes Societies guideline for the management of diabetic ketoacidosis