key: cord-0776308-b6wzpy80 authors: Ningthoujam, Ramananda; Khomdram, Deepa title: WHO statement- “Older people are at highest risk from COVID-19”: Should the hypothesis be corroborated or rejected? date: 2020-06-16 journal: Med Hypotheses DOI: 10.1016/j.mehy.2020.109896 sha: c2ad0b038cbb1c9fc5207060c0222dd2f2d216e8 doc_id: 776308 cord_uid: b6wzpy80 Coronavirus COVID 19 has become a threat to mankind affecting millions of people worldwide. United States, Italy and Spain has the highest number of Coronavirus cases as of April 30, 2020. According to World Health Organization (WHO) statement- “Older people are at highest risk from COVID-19”. However, in contrast to the statement, some new studies and findings have come to light. And this has created confusion in our mind as to whether the hypothesis should be corroborated or rejected. Title (20 words): WHO statement-"Older people are at highest risk from COVID-19": Should the hypothesis be corroborated or rejected? Name(s) of the author(s) with the highest academic degree (Kindly provide for each author. All the fields given in the table below are mandatory. Please add more rows if you need to include more authors. Please list the authors in the order of contribution and indicate corresponding author using an asterisk (*) at the end of the name. The corresponding author must be the one making the submission). WHO statement-"Older people are at highest risk from COVID-19": Should the hypothesis be corroborated or rejected? Dear Editor, Coronavirus COVID 19 has become a threat to mankind affecting millions of people worldwide i,ii . United States, Italy and Spain has the highest number of Coronavirus cases as of April 30, 2020 iii,iv,v . According to World Health Organization (WHO) vi statement-"Older people are at highest risk from COVID-19". However, in contrast to the statement, some new studies and findings have come to light. And this has created confusion in our mind as to whether the hypothesis should be corroborated or rejected. A well-known literature published by Chinese Center for Disease Control and Prevention vii , found that older people are found to be at highest risk from COVID-19. The facts and figures of COVID 19 fatality rate by age in mainland China can be found online viii . In mainland china, 80 percent of all deaths occurred among people aged 60 and above as of February 11, 2020 ix . Wu Z and McGoogan x also reported that old age, cardiovascular disease, diabetes, chronic respiratory disease, hypertension, and cancer were all associated with an increased risk of death in mainland china. The same pattern in also observed in Italy xi where more than 60 per cent of total population is over 40 years of age. According to the reports, Italy has the world's highest number of deaths xii and it is believed that the higher percentage of older person may have contributed to more infections and deaths in Italy with regards to the novel coronavirus. In Italy, approximately 85 percent were patients aged 70 years and older xiii . In United Kingdom, "25% of people in the United Kingdom are designated as high risk including all adults aged over 70 and those with underlying health conditions such as respiratory and cardiovascular disease, and cancer" (doi.org/10.1136/bmj.m1198). In New York city, as of April 14, 2020; older person with previous underlying illnesses like Diabetes, Lung Disease, Cancer, Immunodeficiency, Heart Disease, Hypertension, Asthma, Kidney Disease, and GI/Liver Disease are more vulnerable to COVID 19 compared with no underlying illness xiv . Japan has the world`s oldest population with 28.4 percentage of old people. According to 2014 estimates, 33.0% of the Japanese population is above the age of 60, 25.9% are aged 65 or above, and 12.5% are aged 75 or above. However, the number of COVID 19 cases in older people is less compared to younger people xv . On the contradictory, in India, an age-wise analysis of 1809 coronavirus patients show that most of the infected person belong to the age group of 21-40 (42 %), 83% of India's coronavirus patients are below the age of 50 xvi . This result shows that in India younger generation are at higher risk of contracting the disease. Facts and figures are published in the India Today newspaper dated April 4, 2020 xvii . Some of the list of countries with highest number of older people (65+ years and above) with COVID 19 most vulnerable age group is represented in Table 1 . Out of 29 countries, only 10 countries are having more risk in older people. This finding made us ponder upon the statement "Older people are at highest risk from COVID-19, to either corroborate or reject the hypothesis. To conclude, COVID 19 can affect all age group irrespective of whether the individual is young or old. Therefore, the statement by World Health Organization, "Older people are at highest risk from COVID-19" is still conflicting. Therefore, in depth research is required before making such claims as this may piles up the mental pressure to individuals. There have been cases whether people believed to be suffering from COVID 19 committing suicide in India xviii,xix,xx , Bangladesh xxi , frontline medical doctor from New York xxii , and German finance minister; Thomas Schafer xxiii . As of now, it would be more apt to state that "People with chronic health conditions are at highest risk from COVID 19" as strong immunity is the key weapon to fight against Covid-19. Competing interests: We have nothing to disclose. References iii Yen Nee Lee (April 1, 2020) .US, Italy and Spain have the most coronavirus cases. These charts show their infection curves. https://www.cnbc.com/2020/04/01/charts-show-the-coronavirus-spike-in-us-italy-and-spain.html (Accessed on April 14, 2020) iv https://www.statista.com/page/COVID-19-coronavirus (Accessed on April 24, 2020) v https://www.worldometers.info/coronavirus/? (Accessed on April 26, 2020) vi World Health Organization, Europe (April 2, 2020).Statement -Older people are at highest risk from COVID-19, but all must act to prevent community spread. http://www.euro.who.int/en/health-topics/health-emergencies/coronaviruscovid-19/statements/statement-older-people-are-at-highest-risk-from-covid-19,-but-all-must-act-to-prevent-communityspread vii Chinese Centre for Disease Control and Prevention (2020 Study: Elderly Most at Risk From The Coronavirus Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases from the Chinese Centre for Disease Control and Prevention Similarity in case fatality rates (CFR) of COVID-19/SARS-COV-2 in Italy and China COVID-19 Dashboard by the Centre for Systems Science and Engineering (CSSE) Age, Sex, Existing Conditions of COVID-19 Cases and Deaths Patients profile of coronavirus disease COVID-19) cases in Japan as of 42% of coronavirus patients in 21-40 age bracket: Govt 83% of India's coronavirus patients are below the age of 50: Health ministry data Delhi: Suspected coronavirus patient commits suicide by jumping off 7th floor of Safdarjung Hospital Medical student serving Covid-19 cases found dead in Chennai hostel, cops suspect suicide One Covid-19 patient commits suicide at hospital, 8 new cases in Karnataka First COVID-19 suicide case in Bangladesh due to fear of COVID-19 and xenophobia: Possible suicide prevention strategies New York Doctor on Front Lines of Coronavirus Pandemic Dies By Suicide | NBC Nightly News Source of support: None