key: cord-0774087-9ohwlouf
authors: Rokni, Ghasem Rahmatpour; Gholami, Amir; Kazeminejad, Armaghan; Zakariaei, Zakaria; Layegh, Mohsen; Patil, Anant; Goldust, Mohamad
title: The relationship between stress and vitiligo during COVID‐19 pandemic
date: 2021-10-21
journal: J Cosmet Dermatol
DOI: 10.1111/jocd.14429
sha: 771cb0477ea7d46d65dbd15c135f7c6a703d9e87
doc_id: 774087
cord_uid: 9ohwlouf

nan

Sir, Vitiligo is the most common acquired depigmentary disorder characterized by the development of pale while spots that can occur on any part of skin or mucous membrane. This condition affects almost 0.5% of the world's population and is more common in black people. 1 Although exact pathogenesis is not well understood, two important factors, that is, increased oxidative stress and autoimmunity, are implicated in its development. Melanocyte apoptosis and the production of cytotoxic T cells due to oxidative stress are suggested to play a role in the destruction of melanocytes. it seems prudent to hypothesize that COVID-19-induced stress (both psychological and oxidative stress) may trigger the development of vitiligo in susceptible patients. We strongly feel that patients with known risk factors for vitiligo should be carefully followed and counseled for stress management during COVID-19 pandemic. We also suggest that further studies analyzing the relationship between the pathogenesis of COVID-1 19 and vitiligo are necessary.

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