key: cord-0765605-qaq8k65c
authors: Baptista, João Pedro Ribeiro; Wozniaki, Natalia; Cassi Junior, Helio Vida; Neves, Gabriela Duarte; Boettcher, Ivan Schneider; Dall'Oglio, Ana Claudia; Tavares, Fabiana Sanchez; Gastal, Gabriela Roncone; Schwingel, Fabiano Luis; de Lacerda, Marcelo Pitombeira
title: Severity and One-Year Cumulative Incidence of COVID-19 Among Inpatients with Haematologic Malignancies
date: 2022-05-02
journal: J Hosp Infect
DOI: 10.1016/j.jhin.2022.04.011
sha: d5022e3976c0c7932ffa57b7803e9c63b56d9a3a
doc_id: 765605
cord_uid: qaq8k65c

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COVID-19 presents complex healthcare challenges in assisting patients with chronic diseases and cancer. [1, 2] . Haematologic malignancies (HM) are highly associated with severe COVID-19 due to immune effects of both diseases and treatments [3] [4] [5] . Mortality rate of COVID-19 has been estimated at around 1-2% in the general population and 21%-62% for HM patients [1, [3] [4] [5] [6] . Despite universal healthcare and a celebrated infectious diseases program, Brazil has seen recurring COVID-19 outbreaks and an alarmingly high case-fatality ratio, posing a threat to at-risk populations [6] [7] [8] .

Occurrence of COVID-19 in HM inpatients jeopardizes the possibility of cancer cure or control [2] [3] [4] [5] . To assess the incidence and severity of COVID-19 among HM inpatients, we performed a retrospective analysis of patients admitted between April This study has several limitations, from its single-centre retrospective nature, to the lack of routine SARS-CoV-2 testing on patient admissions, single-bed HEPA- 

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