key: cord-0762689-g4696xvh
authors: Lee, Daniel Yu; Wu, Horng‐Jiun; Cheng, Kai‐Chun; Chang, Yo‐Chen
title: Disc edema in one eye and central serous chorioretinopathy in the other eye shortly after AstraZeneca COVID‐19 vaccination
date: 2021-11-16
journal: Kaohsiung J Med Sci
DOI: 10.1002/kjm2.12473
sha: 9de248758461e5e346dbd6af28c2ca6bd072c5e3
doc_id: 762689
cord_uid: g4696xvh

nan

Dear Editor, Ocular adverse effects associated with various types of vaccine, mainly including optic neuropathy and uveitis have been widely reported for several decades. 1 The commonly reported include vaccines for hepatitis B virus (HBV; 40.5%), human papillomavirus (HPV; 15.6%), and influenza virus (9.7%). 2 Probable mechanisms include direct infection of the attenuated pathogen, molecular mimicry resulting hypersensitivity, and adjuvants-induced inflammation. 2 Here, we present a case who developed optic disc edema in one eye and central serous chorioretinopathy (CSC) in the other eye shortly after receiving COVID-19 vaccine. Figure 1G ) or serous detachment (OS; Figure 1H ). BCVA was 20/20 in both eyes and the patient had no ocular symptoms remaining.

Various types of vaccine against COVID-19 with different mechanisms are now available. Of these, viral vector vaccine against COVID-19 from AstraZeneca recently confirmed that it may induce inflammatory disease, such as immune thrombotic thrombocytopenia. 3 We present a case of disc edema in the right eye and CSC in the left eye shortly after the first dose of AstraZeneca COVID-19 vaccine.

To the best of our knowledge, this is the first case report of different 

Impfschäden am Auge

Vaccineassociated uveitis

Thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination

Bilateral acute macular Neuroretinopathy after vaccination against SARS-CoV-2

Bilateral multifocal choroiditis following COVID-19 vaccination

All authors declare no conflict of interest.Daniel Yu Lee 1 Horng-Jiun Wu 1