key: cord-0762597-xqz2ntc4 authors: Salvagno, Gian Luca; Henry, Brandon M.; Pighi, Laura; De Nitto, Simone; Montagnana, Martina; Lippi, Giuseppe title: SARS-CoV-2 Omicron infection is associated with high nasopharyngeal viral load date: 2022-02-26 journal: J Infect DOI: 10.1016/j.jinf.2022.02.025 sha: 25a9b6c32c9d37995028872016cbe959a9f5a8cf doc_id: 762597 cord_uid: xqz2ntc4 nan corresponding periods of years 2021 and 2022 (i.e., between 3-9 January), characterized by local prevalence of Alpha (>95%; January 2021) and Omicron (>90%; January 2022) SARS-CoV-2 variants, respectively. Briefly, the study population consisted of all patients with a positive SARS-CoV-2 test performed between 3-9 January 2021 or 2022, respectively. Routine nasopharyngeal samples were collected according to standardized practice in subjects referred to the Pederzoli Hospital of Peschiera del Garda (Italy) for undergoing routine SARS-CoV-2 testing for presenting symptoms of In conclusion, the results of our retrospective analysis provide convincing support to the suggestion that aerosols released by patients infected by SARS-CoV-2 Omicron variant may contain higher viral particles than those released by subjects infected with previous SARS-CoV-2 strains, thus providing a solid biologic background to justify enhanced transmissibility of this new linage and higher prevalence of upper respiratory tract symptoms reported in other studies [3, 4] . None declared. High amounts of SARS-CoV-2 in aerosols exhaled by patients with Omicron variant infection Evaluation of three commercial assays for SARS-CoV-2 molecular detection in upper respiratory tract samples Influence of immune escape and nasopharyngeal virus load on the spread of SARS Epub ahead of print Is SARS-CoV-2 Omicron (B.1.1.529) variant causing different symptoms?