key: cord-0757525-fdwd99ah
authors: Hajra Martínez, Ismael El; Pérez, Lucia Relea; Moya, Marta Calvo
title: Presence of SARS-Coronavirus-2 in the ileal mucosa: another evidence for infection of GI tract by this virus
date: 2020-08-07
journal: Gastroenterology
DOI: 10.1053/j.gastro.2020.05.101
sha: addf3d22ec09e3fd58919f6e9905e726c8a4b514
doc_id: 757525
cord_uid: fdwd99ah

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abdominal CT scan, a thickening of the terminal ileum was observed suggesting the presence of acute ileitis. The patient received empirical treatment with ciprofloxacin and metronidazole without any improvement. Microbiological stool examinations were negative, also for SARS-CoV-2 rRT-PCR test. On

April 29 th , the study was completed with an ileo-colonoscopy with ileal biopsy. The mucosa of ileum and colon was macroscopically normal, and the biopsy showed no damage. However, RT-PCR test on ileal tissue was positive for SARS-CoV-2 RNA. We repeated the SARS-CoV-2 rRT-PCR test on nasopharyngeal swab and it again came back negative. The patient improved over the next few days without any specific treatment.

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