key: cord-0757271-podw2l3q authors: Hoshina, Yoji title: E‐cigarette or vaping product use‐associated lung injury: A great COVID‐19 mimicker in young adult date: 2021-10-25 journal: Clin Case Rep DOI: 10.1002/ccr3.5016 sha: b219dff30405ab40bb52c18c4e9172e083f8cd15 doc_id: 757271 cord_uid: podw2l3q EVALI and COVID‐19 share similar clinical and imaging features. Assessing the vaping or e‐cigarette use history and conducting urine toxicology tests for high‐risk patients are important with increasing COVID‐19 cases in young adults. A 20-year-old unvaccinated man presented with a 3-day history of dyspnea and fever. He was tachycardic (heart rate of 160/min) and tachypneic (respiratory rate of 20/min) with oxygen saturation of 93% on room air, body temperature of 37.9°C, and bibasilar crackles were noted. Initial tests were remarkable for leukocytosis (19.0 × 103/μL) and bilateral diffuse consolidation on chest radiography. Chest computed tomography (CT) with contrast showed diffuse, bilateral subsegmental ground-glass opacities ( Figure 1 ). The SARS-CoV-2 nasopharyngeal swab polymerase chain reaction test was negative. He admitted to occasionally using THC-containing e-cigarettes. Urine toxicology test was positive for THC. The Pneumococcal and Legionella urine antigen tests, rapid influenza tests, respiratory viral panel tests, Mycoplasma IgM antibody, HIV, and blood cultures were negative. We diagnosed him with e-cigarette or vaping use-associated lung injury (EVALI). EVALI and COVID-19 have similar substantial clinical features. Although COVID-19 was the most likely diagnosis, given the patient's unvaccinated status, COVID-19 test was negative. Through direct questioning regarding ecigarette, we could suspect EVALI as a possible diagnosis. This case highlights the diagnostic challenge of EVALI, especially in the current context of the COVID-19 pandemic. The median age of EVALI is reported as 21 years old (range 15-53). 1 Assessing the social history, including vaping or e-cigarette use and conducting urine toxicology tests for those with high risk, is essential with increasing COVID-19 cases among young adults. 2 ACKNOWLEDGEMENT Nothing to disclose. None. Y Hoshina collected data and information and also writer of the present work. Informed consent was obtained from the patient. Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. How to cite this article: Hoshina Y. E-cigarette or vaping product use-associated lung injury: A great COVID-19 mimicker in young adult. Clin Case Rep. 2021;9:e05016. https://doi.org/10.1002/ccr3.5016 F I G U R E 1 Chest computed tomography with contrast enhancement shows bilateral patchy ground-glass pulmonary opacities, primarily with a peripheral distribution Pulmonary illness related to E-Cigarette use in illinois and Wisconsin -Final report COVID-19 trends among Persons aged 0-24 years -United States Yoji Hoshina https://orcid.org/0000-0003-0228-664X