key: cord-0750849-8n2w7azb authors: Sookaromdee, Pathum; Wiwanitkit, Viroj title: Temporal metabolic response and mRNA COVID-19 vaccination date: 2021-09-18 journal: Ann Nucl Med DOI: 10.1007/s12149-021-01679-4 sha: e36d46139e67616beea9a95490bd61d3c82889d3 doc_id: 750849 cord_uid: 8n2w7azb nan Dear editor, we would like to share ideas on the publication "Temporal metabolic response to mRNA COVID-19 vaccinations in oncology patients [1] ." Advani et al. concluded that "Consideration should be given to performing FDG PET at least 2 weeks after the COVID-19 vaccine. [1] ." This report can confirm that both immunological and metabolic responses occurred at lymph node following COVID-19 mRNA vaccination. Waiting might be a good practice. However, the problem might still exist after 2-week period of waiting and it is sometimes not possible to have a long waiting. To avoid interference in medical imaging for cancerous case, in a recent report, it is recommended for "administering the vaccine in the arm contralateral to a unilateral cancer [2] ." Temporal metabolic response to mRNA COVID-19 vaccinations in oncology patients COVID-19 vaccination-related uptake on FDG PET/CT: an emerging dilemma and suggestions for management