key: cord-0747378-10rwkzcz
authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj
title: Response to case report on myocarditis and pericarditis after COVID‐19 vaccination
date: 2021-09-27
journal: J Am Coll Emerg Physicians Open
DOI: 10.1002/emp2.12559
sha: 4eecc47af5698df1d24e459270fac85243b4568c
doc_id: 747378
cord_uid: 10rwkzcz

nan

Dear Editor,

We would like to comment on the publication "Myocarditis and pericarditis after vaccination for COVID-19." Hudson et al reported on an interesting case study and concluded that, "Although the majority of reported cases are coming from the lay press as the number of reports increases there is growing concern for at least an association between COVID-19 vaccination and subsequent myocarditis." 1 Hudson et al showed clinical data to support the existence of the cardiac problem.

In the present case, a presumptive diagnosis of myocarditis is based on clinical history and laboratory findings. No cardiac imaging or pathological study is done. Based on the case report, the cardiac problem is confirmed, but the pathogenesis of the cardiac problem is not clear.

Hudson et al discussed many potential mechanisms of the cardiac problem, including hypersensitivity, inflammatory process, or inappropriate immune activation. 1 We agree that immunopathological processes might induce the problem. However, no laboratory evidence exists to confirm this. If there is a hypersensitivity problem, some 

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