key: cord-0738515-mlffcwnj
authors: Tonon, David; Simeone, Pierre; Lagier, David; Bourenne, Jérémy; Velly, Lionel
title: Association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19
date: 2021-02-06
journal: Anaesth Crit Care Pain Med
DOI: 10.1016/j.accpm.2021.100812
sha: b06b1a3f7ba27ff26c8418e6dd7ec813201c5a95
doc_id: 738515
cord_uid: mlffcwnj

nan

Recently Hoiland et al. 1 published a study which suggests a strong correlation between ABO blood group and severity of COVID-19. In this works, the critically ill COVID-19 patients with blood group A or AB were at increased risk for mechanical ventilation, continuous renal replacement therapy (CRRT), and prolonged ICU stay compared to patients with blood group O or B. Such associations have already been reported for pulmonary infection related to severe acute respiratory syndrome coronavirus (SARS-CoV) 1 and 2. 2 However, we would like to comment on these results in light of our data. These findings are different from those reported by our colleagues, and we discuss some points.

First, one of the most frequently discussed argument of ABO blood typing topic is the different distribution of ABO groups according to local populations which could influence the Some studied reported similar findings to ours. Latz et al. 3 found that blood type was not associated with risk of intubation or death in patients with COVID-19 acute respiratory distress syndrome. In a recent meta-analysis, Bing-Bin Wu et al. 4 found no statistical difference in COVID-19 severity between each ABO blood group . All these findings could therefore waive local considerations of ABO blood group distribution.

Second, Hoiland et al. 1 present a high proportion of patients requiring CRRT (n=12, 32%) in the A or AB groups. It has been proven that patients with renal involvement had higher overall mortality compared with patients without. 5 One of the confounding factors that could explain this result might be a difference in treatment protocol between the two groups. 

The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19

ABO Blood Group and Susceptibility to Severe Acute Respiratory Syndrome

Blood type and outcomes in patients with COVID-19

Association between ABO blood groups and COVID-19 infection, severity and demise: A systematic review and meta-analysis