key: cord-0733912-03s404s5
authors: Luciani, Lorenzo G.; Gallo, Fabrizio; Malossini, Gianni
title: Re: Jan-Niclas Mumm, Andreas Osterman, Michael Ruzicka, et al. Urinary Frequency as a Possible Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.05.013: Severe Involvement of the Urinary Tract During COVID-19 Infection
date: 2020-06-12
journal: Eur Urol
DOI: 10.1016/j.eururo.2020.06.006
sha: be8121222fd1d3edb434f3c20ee760956a1f3425
doc_id: 733912
cord_uid: 03s404s5

nan

Mumm et al [1] reported that urinary frequency might be a symptom of SARS-CoV-2. This assumption is based on the finding that the bladder urothelium, as well as the kidney, harbors cells expressing ACE2, the receptor for the viral spike protein [2,3]. Our experience appears to confirm their suspicion, further suggesting that the urinary tract may become the target of life-threatening involvement by SARS-CoV-2.

We report three cases of gross hematuria admitted to two hospitals in Northern Italy between 

The authors have nothing to disclose. 

Urinary frequency as a possible overlooked symptom in COVID-19 patients: does SARS-CoV-2 cause viral cystitis? Eur Urol