key: cord-0733291-rjozlfor authors: Zhou, Suizi; Liu, Yibin; Xue, Jianrong; Tang, Jun; Yu, Qingqing; Qu, Shenhong; Zhang, Shaojie; Mo, Binyu; Li, Jihui; Liu, Yinhong; Yang, Yueying; Wang, De‐Yun; Qiu, Qianhui title: Sustained impact of subcutaneous immunotherapy among patients with allergic rhinitis who experienced treatment delay due to the COVID‐19 pandemic: A multicenter, two‐arm, real‐world study date: 2022-03-01 journal: Clin Transl Allergy DOI: 10.1002/clt2.12122 sha: 32606cc964424d93a7e1fa57729658ebe1d1bc9b doc_id: 733291 cord_uid: rjozlfor nan Sustained impact of subcutaneous immunotherapy among patients with allergic rhinitis who experienced treatment delay due to the COVID-19 pandemic: A multicenter, two-arm, real-world study To the editor, Subcutaneous immunotherapy (SCIT) is highly effective for seasonal pollinosis and perennial disease in patients with mite allergy. 1 SCIT usually involves administering a gradually increasing dose of the specific allergens to allergic patients until the effective dose is reached then followed by administering the maintenance doses for 3 years or more. 2 The proportion of patients without depressed of SCIT scheduled and delayed were 28.11% and 66.86% at V0, and 60.95% and 79.52% at V1; mildly depressed patients were 60.33% and 29.33% at V0, 32.35% and 19.05% at V1; moderately depressed patients were 11.16% and 3.81% at V0, 5.80% and 1.43% at V1 (all P < 0.0001). Severely depressed patients were 0.40% and 0.90% at V0 and V1 respectively from SCIT scheduled, but none of them from SCIT delayed ( Figure 1D ). Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper Role of IL-35 in sublingual allergen immunotherapy Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines Clinical outcomes and adverse effect monitoring in allergic rhinitis Prevalence and predictors of anxiety and depressive symptoms among patients diagnosed with oral cancer in China: a cross-sectional study COVID-19: pandemic contingency planning for the allergy and immunology clinic https://orcid.org/0000-0002-8457-6044