key: cord-0731129-omf2nsgg authors: Ciccarese, Giulia; Drago, Francesco; Boldrin, Samuele; Pattaro, Matilde; Parodi, Aurora title: Sudden onset of vitiligo after COVID‐19 vaccine date: 2021-11-15 journal: Dermatol Ther DOI: 10.1111/dth.15196 sha: 4c5bd99285c333954e5a99e43fb4b25932e66ef2 doc_id: 731129 cord_uid: omf2nsgg nan The patient's medical history was unremarkable, and she did not take any drug. She had family history of vitiligo (father) but she had never suffered from it before. The white macules were clinically consistent with vitiligo and examination under wood lamp Since vitiligo is a common pigmentary disorder afflicting 0.5%-2% of the world population 8 and COVID vaccination nowadays is a common practice, the possibility that the onset of vitiligo after vaccination is just a coincidence should also be considered. However, the temporal relationship between the vaccine and development of the disease and the instances of autoimmune phenomena manifesting after COVID-19 vaccination, 1, 2, 5, 6 suggest that the vaccine could play a role in triggering vitiligo. Induction and exacerbation of subacute cutaneous lupus erythematosus following messenger-RNA or adenoviral-vector based SARS-CoV-2 vaccination Acute autoimmune-like hepatitis with atypical anti-mitochondrial antibody after mRNA COVID-19 vaccination: A novel clinical entity? Vitiligo in a COVID-19-vaccinated patient with ulcerative colitis: coincidence? Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registrybased study of 414 cases Vaccination and autoimmune diseases: is prevention of adverse health effects on the horizon? New-onset vitiligo following mRNA-1273 (Moderna) COVID-19 vaccination Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection What's old, what's new The authors declares there is no potential conflict of interest. Giulia Ciccarese conceived of the presented idea; Giulia Ciccarese wrote the manuscript with support from Samuele Boldrin and Francesco Drago; Matilde Pattaro and Aurora Parodi provided critical feedback; all authors discussed the results and contributed to the final manuscript. The data that support the findings of this study are available from the corresponding author upon reasonable request.