key: cord-0729555-16hf39hh
authors: Naderian, Mohammadreza; Sheikhy, Ali; Ghorashi, Seyyed Mojtaba; Tajdini, Masih; Sadeghian, Saeed; Hosseini, Kaveh
title: Fluid Management in acute cardiac condition and superimposed COVID-19 infection. Do we need a careful revision?
date: 2021-04-03
journal: Caspian J Intern Med
DOI: 10.22088/cjim.12.3.356
sha: 43d1b50507114c5053bc63d61b693f9978079286
doc_id: 729555
cord_uid: 16hf39hh

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We compared these groups of patients in our database; 20 patients with prerenal azotemiadefined as the ratio of blood urea nitrogen to creatinine of more than 20, after exclusion of secondary causes -at the time of admission and 30 patients without prerenal azotemia (table 1) .

Five patients were excluded from the study because they received hemodialysis as renal replacement therapy before admission, and there were no accurate measures for detecting prerenal azotemia.

Regarding the background prerenal azotemia, they had not received enough fluids in the first 24 hours. The prerenal azotemia group eventually experienced more death (50% compared with 13.3%) and more death composites, acute renal failure, and intubation (60% compared with 26.5%). Further investigation of our data revealed that the amount of fluid administration was inversely associated with hospitalization length (Spearman's rho correlation coefficient: -0.31, p0.06). There were no significant differences between the amount of serum therapy in the dead and survived patients, intubated and non-intubated patients, and ARDS and non-ARDS patients.

This study showed that high BUN to creatinine ratio was associated 

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