key: cord-0729365-8yodjeeo
authors: Martinez-Garcia, Miguel Angel; Aksamit, Timothy R.; Aliberti, Stefano
title: BRONQUIECTASIAS COMO SECUELA CRÓNICA DE LA NEUMONÍA POR SARS-COVID-19: SE REQUIEREN ESTUDIOS EN EL FUTURO
date: 2021-04-26
journal: Arch Bronconeumol
DOI: 10.1016/j.arbres.2021.04.021
sha: fc4ca46a1f09c5fef36513db4ab18476aa1c1cb4
doc_id: 729365
cord_uid: 8yodjeeo

nan

Although this is a relevant finding since it probably implies a permanent alteration to the lung parenchyma, different circumstances should be highlighted. On the one hand, the percentage of patients who already had bronchiectasis prior to COVID-19 pneumonia, as well as the role of the viral infection in determining them are not known. On the other hand, the etiology of these dilated airways is also relatively unknown, in many cases may be due to traction in the context of pulmonary fibrosis. This hypothesis is supported by the results obtained by Han et al (5) , who observed that the majority of patients who develop bronchiectasis also present with pulmonary fibrotic changes presumably secondary to the COVID-19 pneumonia. In this respect, the nature of the inflammatory component of this bronchiectasis, its potential to lead to recurrent bronchial infection and inflammation by potentially pathogenic microorganisms and, therefore, its potential to worsen prognosis, are unknown. Likewise, it is unknown whether this bronchiectasis is merely a radiological finding or whether it can be associated to respiratory symptoms requiring and progressive change over time. Finally, the specific prognostic factors for the development of bronchiectasis are also unknown, although in this same study the authors observed that the following were prognostic factors for subsequent fibrotic sequelae: age greater than 50 years; heart rate at admission higher than 100 bpm; more than 17 days of hospitalization; a need for non-invasive mechanical ventilation; presence of an acute respiratory distress syndrome, and a greater initial involvement on CT scan (5) . We can speculate that some of these risk factors could be also considered as relevant for the development of bronchiectasis in these patients but this question requires additional investigation. However, the potential of these findings should not be underestimated given the known association between a history of viral infections, including measles, respiratory syncytial virus, influenza 

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