key: cord-0728814-6nlo9t6y authors: Lippi, Giuseppe; Henry, Brandon M.; Sanchis‐Gomar, Fabian; Mattiuzzi, Camilla title: Searching for a clinically validated definition of “asymptomatic” COVID‐19 infection date: 2021-08-13 journal: Int J Clin Pract DOI: 10.1111/ijcp.14085 sha: 67ef8efdc4f2b3e62f339030c37f02039a8b6daf doc_id: 728814 cord_uid: 6nlo9t6y nan Dear Editor, We read with interest the article of Gormeli Kurt and Gunes, 1 who emphasised that timely detection and isolation of asymptomatic patients with coronavirus diseases 2019 (COVID-19) has primary importance for contrasting the spread of the ongoing pandemic outbreak. According to their study design, patients were defined asymptomatic when they received a definitive molecular diagnosis of COVID-19 without presenting symptoms such as fever, cough and myalgia. The issue of defining, and hence accurately identifying, asymptomatic infections remains a major drawback for purposes of immediate isolation and/or timely clinical management. 2 Retrospective analysis of asymptomatic COVID-19 patients presenting to emergency department Towards an accurate and systematic characterisation of persistently asymptomatic infection with SARS-CoV-2