key: cord-0728293-l1okt3lm authors: pathak, Mamta; kumar patel, Shailesh; rana, Jigyasa; tiwari, Ruchi; dhama, Kuldeep; sah, Ranjit; Rabaan, Ali a.; bonilla-aldana, Katterine; Rodriguez-morales, Alfonso j. title: Global Threat of SARS-CoV-2/COVID-19 and the Need for More and Better Diagnostic Tools date: 2020-04-15 journal: Arch Med Res DOI: 10.1016/j.arcmed.2020.04.003 sha: 640fcae45a4a7ecb14294fa4f27f56c429f55355 doc_id: 728293 cord_uid: l1okt3lm nan , discussing concerning questions, and particularly the urgent, evidence-based, and practical measures needed. We would like to compliment, and add a synthesis of the current technological advances on emerging approaches to improve control and particularly diagnosis of this emerging pandemic ( Figure 1 ). Now with more than 1 million cases, the COVID-19 pandemic is leading to substantial economic losses, psychological and social impacts. Caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), this emerging disease has been extended to more than 200 countries facilitated by inappropriate and insufficient preventive measures along with unrestricted travel (2) . In a study, artificial intelligence (AI) using a three-dimensional deep learning model was reported highly sensitive and specific for the diagnosis of COVID-19 from CT images (Figure 1) . A combination of disease history, clinical manifestations, molecular tests, and radiological findings is crucial and imperative for making an accurate and useful diagnosis. Moreover, there is always a need for rapid, accurate, and highly sensitive diagnostic assays to stop the menace created by the worldwide spread of this virus by early detection and follow up of subsequent timely implementation of appropriate prevention, control and mitigation strategies. None. None. Practical Strategies Against the Novel Coronavirus and COVID-19-the Imminent Global Threat Going global-Travel and the 2019 novel coronavirus Rapid colorimetric detection of COVID-19 coronavirus using a reverse tran-scriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic plat-form: iLACO Point-of-Care RNA-Based Diagnostic Device for COVID-19