key: cord-0720158-p1rsz8fk
authors: Tartari, Federico; Spadotto, Alberto; Zengarini, Corrado; Zanoni, Rossana; Guglielmo, Alba; Adorno, Alexander; Valzania, Cinzia; Pileri, Alessandro
title: Herpes zoster in COVID‐19‐positive patients
date: 2020-06-12
journal: Int J Dermatol
DOI: 10.1111/ijd.15001
sha: f14b2927003e86c021c0c5ee3941687940de99fb
doc_id: 720158
cord_uid: p1rsz8fk

nan

demic by the World Health Organization (WHO). 1 The disease was defined as COVID-19 (Coronavirus Disease 2019) 1 and principally affects the respiratory tract with a clinical scenario ranging from common cold to severe pneumonia. Diagnosis of COVID-19 disease is made on the grounds of clinical signs (fever, malaise, fatigue, dry cough, rhinorrhea, ageusia, anosmia, anorexia, and dyspnea), vital signs (fever >37.5°C, pulse oximetry saturation <98%), and radiological findings (chest CT scan for the presence of ground glass opacity). 2 The clinical scenario differs with most patients only needing supportive care, while others require admission to an intensive care unit (ICU) for invasive mechanical ventilation. 2 In Italy, the first person-to-person transmission of the SARS-CoV-2 was recorded on February 21, 2020, and to date (04/28/2020) the number of COVID-19 positive subjects is more than 100,000.

The number of people requiring hospitalization and ICU is 30,000 and 3,000, respectively. At the time of writing, the number of positive cases has peaked in Italy. However, little is known on the cutaneous manifestations of COVID-19-positive patients. [3] [4] [5] We aim to expand our knowledge by reporting four zoster infections in COVID-19-positive patients observed between March and April 2020. Four cases were retrieved, three female, one male, median age 70.5 years (range 68-74). Three were admitted to the ICU and required mechanical ventilation along with hydroxychloroquine and tocilizumab administration in one patient (for details, see Table 1 ). All three patients developed a necrotic herpes zoster on the sec- 

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