key: cord-0707367-q21duaah authors: Naseef, Hani A.; Al-Shami, Ni’meh A.; Hadba, Lilian S. Abu; Humos, Leen A.; Shaheen, Ruba N.; Mitwasi, Tanya T.; El-Khairy, Lina title: Knowledge, attitudes, and practices about coronavirus disease (COVID-19) among Birzeit University students: a cross-sectional study date: 2021-11-08 journal: Z Gesundh Wiss DOI: 10.1007/s10389-021-01665-0 sha: 17bc5f43a154454f24305187eef304a2b46d59b2 doc_id: 707367 cord_uid: q21duaah AIM: COVID-19, the novel coronavirus, has been characterized as a pandemic, as it spreads all over the world and has so far infected more than 20 million worldwide. In Palestine, the first seven cases were documented on March 5 2020, followed by the declaration of the state of emergency. This study aimed to assess knowledge, attitudes and practices toward COVID-19 among Birzeit University students. SUBJECT AND METHODS: A cross-sectional study was carried out; a questionnaire was developed based on the WHO, CDC, and ECDC recommendations. The questionnaire was distributed online and filled out by Birzeit University students. Chi-square testing was performed to check for significant association between KAP (knowledge, attitude, and practices) and different socio-demographic variables. Binary logistic regression was performed to identify and control the confounding factors. Data were analyzed using SPSS (version 22). RESULTS: A total of 665 students have completed the online questionnaire. The mean age was 20.55 ± 3.069 years. Multivariate analysis revealed that males, students from health professions and scientific faculties, and those with highly educated parents had manifested a good knowledge level (GKL) about COVID-19. With regard to students’ practices, fewer negative practices were displayed by students from health professions faculty and the students living at the middle governorate of Palestine, compared to north, south, and Jerusalem dwellers. With regard to the practices, the vast majority of the participants showed a positive and very cautious practice in relation to the COVID-19 epidemic. CONCLUSION: Our results revealed that students had variable knowledge about COVID-19, and the vast majority depended on the official media briefs in Palestine as a source of information. With regard to practices, positive and cautious practices with regard to the COVID- 19 epidemic were carried out by the vast majority of participants. Coronaviruses are a large family of viruses which have been known to cause respiratory infections such as the Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS) and the coronavirus disease 19 (WHO 2020a, b; Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention 2020). COVID-19 was first discovered during an outbreak in Wuhan, China in December 2019 which led to thousands of deaths. Consequently, it spread widely throughout the world, with especially large outbreaks occurring in South Korea, Italy, Iran, the USA, and many other countries (World Health Organization 2020). By July 8, 2020, the virus had reached more than 150 countries, resulting in approximately 12 million infected people, among whom 5 million had recovered and 548,998 had died (WHO 2020a). These alarming levels of spread and severity of the disease have therefore raised the bar for the entire world to manage this stressful crisis and caused the World Health Organization to officially characterize COVID-19 as a pandemic (WHO/Europe 2020). With regard to the symptoms of COVID-19, some infected people may not experience any symptoms, whereas others may have mild symptoms. Around 80% of patients recover without needing any special treatment, while one out of six patients develop more severe symptoms, including but not limited to difficulty in breathing; these patients are most likely to be elderly or with underlying medical conditions, such as high blood pressure, heart problems, or diabetes (ECDC 2020; Wang et al. 2020; Zhang et al. 2020b ) Additionally, young people are not invincible against coronavirus; world data have shown that a large number of patients were young, among whom many needed hospitalization (Chen et al. 2020; Bialek et al. 2020; Escalera-Antezana et al. 2020) . On March 5 2020, the Palestinian authorities announced the first seven cases in the city of Bethlehem, which led to the declaration of a 30-day state of emergency. During this period, further preventative precautions such as quarantine and testing any suspected carriers were undertaken in an attempt to control this pandemic crisis without overwhelming the country's limited financial and healthcare resources. The unavailability of a definitive treatment or vaccine for COVID-19 at that time emphasized the importance of nonpharmaceutical protective and preventive measures as the only means of combating this disease. Knowledge, attitudes, and practices with regard to COVID-19 among the Palestinian community are of immense importance and are critical for the community prevention/ control of this pandemic. The main objectives of this study were to evaluate the knowledge, attitude, and practices (KAP) regarding COVID-19 among students (undergraduate and postgraduate) at Birzeit University in Palestine. This study aims to assess the relationship between students' different socio-demographic characteristics and their effects on their knowledge level, practices, and attitudes with regard to COVID-19. Moreover, this study evaluates the participants' opinions about the performance of the local authorities and their trusted source of information during this pandemic. Evidence-based data from such studies could have an impact on policy decision-makers in the healthcare systems, and perhaps help in designing appropriate strategies to improve the awareness and attitudes with regard to COVID-19 in order to facilitate managing the outbreak in Palestine. An observational analytical cross-sectional study was conducted among students (undergraduate and postgraduate) at Birzeit University in the occupied Palestinian territories between March and April 2020. The targeted respondents were all registered students from different majors (health and non-health professions) at the period of conducting the study, having an ID number and internet services. Any cases of duplication or fabrication in the inserted ID number were excluded. The data were collected through an online distributed questionnaire between March 31 and April 10 2020, as this was considered the only feasible way of distributing the questionnaire during the forced lockdown. The questionnaire was designed and provided using Google Forms under the supervision of IT department personnel. The total population presented was 14,500 students, which is the total number of students registered at Birzeit University. The sample size was 375 as calculated online (Raosoft 2020) using the following equation with 95% confidence level and 5% error margin. where: n Total sample size. N Population size. E Margin of error. About 665 students completed the questionnaire as a selfselectiing sample after filling out their informed consent page online. The study was approved by the IRB committee at Faculty of Pharmacy, Nursing and Health Professions, Birzeit University with reference number BZU-PNH-2006. The questionnaire was formed through a standardized methodology which includes the review of the literature information, group discussion, experts' evaluation, pilot study, and the validation of the final components of the questionnaire (Ishii et al. 2012; Arora et al. 2017 ). However, due to the worldwide lack of published literature regarding the evaluation of knowledge, attitudes, and practice (KAP) with regard to COVID-19 among various society districts, the information was obtained from a comprehensive literature review with regard to the evaluation of KAP toward MERS and SARS (Mbroh 2019; Lau et al. 2003; Bener and Al-Khal 2004; Kim et al. 2016; Yang and Cho 2017; Al-Hazmi et al. 2018; Asaad et al. 2019; Goni et al. 2019) , and from the WHO (WHO 2020c), Centers for Disease Control and Prevention (CDC n.d.) , and European Center for Disease Prevention and Control (ECDC 2019) websites. The questionnaire components were reviewed and evaluated by the researchers' team in a series of meetings. The questionnaire was validated by four multidisciplinary experts panel with proven experience in epidemiology and research field, in order to obtain their input and their critical appraisals with regard to the questionnaire's content relevance and appropriateness. Thence, based on experts' feedback, some sectors of the questionnaire were excluded and re-phrasing of certain questions was considered. Furthermore, a pilot study was distributed among students of different faculties, in order to reveal any drawbacks presented in the questionnaire, where students were requested to complete the questionnaire and give their feedback concerning its clarity, construction, and relevance. Thence, based on students' assessment, some adjustments were made and the final draft was created in Arabic, then translated into English, and then underwent a final review. The final questionnaire was composed of a short overview of the nature and purposes of the study, an assurance conerning the confidentiality of the respondents' responses, and the informed consent form. Then, in four sections to assess the socio-demographics, knowledge, attitudes, and practices of the participants, 45 questions were structured as both open-and closed-ended multiple choice questions. The socio-demographic section consisted of 13 questions regarding gender, age, marital status, major, study year, current place of residence, number of family members, whether any were aged over 60, and parents' educational attainment and the nature of their work. The second section assessed the participants' knowledge of COVID-19 by asking 14 questions about the etiology, host, incubation period, transmission, prevention and control approaches, symptoms, risk group, mortality rate, and information sources. The answers were on the basis of yes and no, with an additional option of 'I don't know'. The third section assessed the students' attitudes towards COVID-19 using a set of ten questions with 'I agree', 'I don't agree', and 'I don't know' as answer options. This section measured agreement or otherwise with the following: invincibility against COVID-19, worry that a family member would get the disease, willingness to seek advice as needed, and preventive measures applied by the local authorities. The fourth section consisted of ten questions; nine of these assessed the students' practice with regard to COVID-19 and the tenth their smoking habits. The questions evaluated the preventive measures taken at the individual level including: self-hygiene, proper coughing or sneezing methods, wearing face masks, keeping a safe distance, limiting presence in public places, limiting travelling between different governorates, and whether they supplied their houses with antipyretics, necessary medications, vitamins, and nutritional supplements. The answers were 'frequently', 'always', 'often', 'rarely', and 'never'. Descriptive statistics were performed to present data; a knowledge scale was developed from the 13 questions that identify the participants' knowledge about the virus, its symptoms, and how to prevent it, with internal consistency (Cronbach α = 0.577). Recoding for questions with more than one answer was done, then counting for the correct answers was performed within 32 items; one score was given for each. A scale was developed and recoded into acceptable knowledge level (AKL), scoring less than 26, and good knowledge level (GKL), scoring 26 to 32. Another scale was developed for participants' practices; recoding for negative items was performed, a count for the positive statements within ten items was done, scored, and recoded into more positive practices (8 to 10 positives) or less positive ones (less than 8). Chi-square testing with 95% confidence interval was performed to identify the socio-demographic variables associated with the knowledge and practice scales. Then a third Chi-square test with 95% confidence interval was performed to assess the association between the knowledge level of respondents and their attitudes. Binary logistic regression analysis was performed to establish the association between knowledge level and more positive practices with the variables that were identified as significant in the bivariate analysis, and to identify and control the confounding factors. All data were analyzed using the Statistical Package for Social Sciences (IBM SPSS Statistics 22). A total of 665 students completed the online questionnaire. The mean age was 20.55 ± 3.069 years, and 488 (73.4%) were females. One hundred and seventy-six (26.5%) of the students were from the pharmacy, nursing, and health professions faculty, and the remainder were from non-medical majors. Three hundred and seventy-nine (59.7%) of the students resided in the middle of the West Bank, with 333 (50.1%) being city residents. More than half of the students (n = 357, 53.7%) were part of a big family consisting of more than six members, and 126 (18.9%) in families which included members over the age of 60. Additionally, 455 (68.5%) of the students had at least one parent who had completed a diploma or higher education, with less than 5% of them working in the health sector (Table 1) . Out of 665 respondents, 495 (74.4%) rated their own knowledge level regarding COVID-19 as good to very good; however, data analysis revealed that only 275 (41.4%) actually had good knowledge level (GKL), whereas 390 (58.6%) had acceptable knowledge level (AKL). In total, 97.6% of respondents knew that COVID-19 is a viral infection that affects the respiratory tract system, 95.8% acknowledged that the median incubation period is between 2-14 day,s and 92.3% responded that it's a curable disease. However, only 46.6% recognized that bats are considered the original host for COVID-19. Respondents' answers concerning COVID-19 transmission approaches revealed acknowledging sneezing or coughing respiratory droplets, touching face, eyes, nose, and mouth with contaminated hands, direct contact with patients, and contact with contaminated surfaces as methods of transmission, with percentages of 92.3%, 89.6%, 87.2%, and 78.5% respectively. Furthermore, 91.6% of respondents knew that approaching pets is not a method for COVID-19 transmission. Concerning COVID-19 symptoms, fever and dry cough were stated in more than 90% of participants' responses, whereas only 56.5% recognized general fatigue as a symptom, and 30.4% believed improperly that flu-like symptoms and nasal congestion were symptoms. When asked about COVID-19 high-risk groups, over 90% of respondents mentioned the elderly, patients with chronic diseases, and immune-compromised patients, while only 12% acknowledged that severe obesity is also considered a high-risk category. As for COVID-19 prevention methods, drinking hot beverages and eating garlic, onions, and pickles were wrongly believed to be the optimal preventive approaches by 44.2% and 15.3% of the answers respectively (Table 2) . Furthermore, 12.9% of participants believed that antibiotics are an optimal method for preventing COVID-19 infection, which is not proven at the time of conducting the study. On the other hand, the majority of the participants (91.1%) believed that personal hygiene is an optimal method for preventing COVID-19 infection. The official media outlets in Palestine (Ministry of Health website and government spokesperson) were the major sources of information about COVID-19 for 79.1% of the participants. A significant percentage (69.6%) of the respondents reported scientific resources as a source of information, followed by media and the social media (65.1% and 46.8% respectively) ( Fig. 1) . As depicted in Table 3 , logistic regression analysis results affirmed that students' extent of knowledge regarding COVID-19 is significantly related to their gender; females manifested lower knowledge levels compared to males (OR = 0.588, p = 0.01). Regarding major specialty, a higher knowledge level of COVID-19 was manifested in scientific faculties (OR = 1.841, p = 0.004) and health professions faculties (OR = 3.462, p < 0.001) in comparison to literary faculties. Additionally, significant results were obtained with year progression; where students in their 4th year of studying or more were more likely to have GKL (OR = 5.562, p < 0.001), then 2nd year students (OR = 2.717, p < 0.001) and 3rd year (OR = 2.249, p = 0.003) compared to 1st year students. As for place of residency, results showed that refugee camps residents were the least likely to have GKL (OR = 0.235, p = 0.016) compared to city citizens. With regards to parental factors, students with both parents having higher educational attainment were more likely to have GKL (OR = 1.931, p = 0.013) compared to their counterparts, whilst students whose mothers worked in non-health related jobs or were unemployed were less likely to have GKL compared to health sector employees (OR = 0.332, p = 0.03 and OR = 0.345, p = 0.04 respectively). As seen in Table 4 , a higher percentage of respondents (90.7%) were worried that a family member would get COVID-19; 84.1% of them remarkably thought that COVID-19 preventative measures should be applied by everyone regardless of their status. In addition, 96.2% of the participants would seek assistance from the responsible authorities if they or a family member develops symptoms of COVID-19. As for the practices applied by the government, 96.5% of respondents considered that the preventative measures taken by the Palestinian government at the beginning were sufficient and done in a timely manner. Table 5 shows that although more than 90% of respondents were worried that a family member might get COVID-19, students with GKL were found to be significantly less likely to be worried (8.7%, p = 0.007). They believed that preventative measures should not be practiced solely by older adults and groups most at risk (91.3%, p < 0.001) in comparison to students with AKL (4.6% and 79.0% respectively). Likewise, participants with GKL were less likely to consider themselves invincible from COVID-19 (56.7%, p < 0.001) than those with AKL (34.4%). Students with GKL were significantly more likely to believe that the attempts of the local authorities will not succeed in curbing the spread of COVID 19 (19.3%) and that they did not have sufficient tools to deal with the pandemic (66.5%) as compared to students with AKL (12.6% and 54.9% respectively). In addition, students with GKL were significantly more likely to believe that the preventive measures taken by the Palestinian government were neither early nor sufficient (54.9% and 38.2%) than students with AKL (52.3% and 33.3% respectively). With regard to the ten positive practices (PP) abided by the individuals for self and others' safety, Table 6 shows that adherence with at least eight practices was observed in 511 (76.8%) of the respondents; these include washing hands and using proper hygiene (97.0%), practicing cough etiquette (95.9%), and avoiding public places and maintaining a safe distance between individuals (93.5% and 79.1% respectively). However, 154 (23.2%) displayed implementation of at least three negative practices. With regard to smoking habits, respondents reported smoking as follows: less frequently (5.3%), same frequency (6.5%), more frequently (2.4%) and cessation (1.8%). (Fig. 2) . Withh regard to the different variables affecting practices towards COVID-19, and based on data obtained by binary logistic regression as presented in Table 7 , numbers showed that females had fewer negative practices compared to males (OR = 0.323, p < 0.001). Other factors influencing the respondents' practices were found to be their major and study year. Negative practices were less likely among health professions faculty participants (OR = 0.631, Fig. 1 p = 0.083) compared to students from literary faculties, whereas postgraduates tended to have fewer positive practices (OR = 3.362, p = 0.004) compared with students in their first year, while no significant differences in practices were found between undergraduates in the other studying years. Moreover, among the variables having an impact on practices was the governorate to which the respondents belong, where middle of the WB revealed the lowest adherence with negative practices (OR = 0.512, p = 0.006) compared with students from Jerusalem and the oPT. Our findings indicate that although less than half of the participants have a good knowledge level with regard to COVID-19, none of the participants was totally unaware of the disease. This could be attributed to conducting the study early in the outbreak in Palestine, and the diverse media coverage of COVID-19 in concurrence with the state of emergency in the country. The relatively low percentage of participants with a good knowledge level in this study is in line with findings of a study conducted among health care workers which reported that knowledge and perceptions of COVID-19 varied across different categories of health care workers but that in general the participants had a poor knowledge level (Bhagavathula et al. 2020a The level of knowledge varied depending on the type of question. For example, almost all therespondents knew that COVID-19 is a viral infection that affects the respiratory tract system, and the majority of them knew the methods of transmission and believed that personal hygiene is the optimal method of preventing COVID-19. However, some practices such as drinking hot beverages, gargling with water, and washing the nose were wrongly believed to be preventative. In addition, around an eighth of the participants believed that antibiotics were an optimal method of prevention; more than half of these participants were from literary faculties. The students from health professions faculties achieved a knowledge level higher than their counterparts'. This could be attributed to these students taking various health-related courses, as well as their involvement in public health campaigns, which in turn enable them to have a better understanding of potentially epidemic infectious diseases such as COVID-19. These findings are consistent with previous studies which reported that students from health colleges had significantly better knowledge than others (Alzoubi et al. 2020; White et al. 2020) , and contradict what was concluded in a study conducted in Jordan, where no significant difference between the mean of knowledge, attitude and practice level was found among medical and non-medical students (Alzoubi et al. 2020) . In accordance with a study conducted in Uganda (Olum et al. 2020) , this study reported that females manifested lower knowledge levels compared to males. Our results are inconsistent with earlier studies which reported that females had a significantly higher score than males (Al-Hazmi et al. 2018; Zhong et al. 2020; Peng et al. 2020) , and one study which reported no significant correlation of gender and specialty with both knowledge and attitude (Khan et al. 2020). It's noteworthy that despite Facebook being the social media application most used by students in Palestine, official media including the Ministry of Health's website, the Government spokesperson, and the scientific resources were found to be the most important sources of information amongst students. This is attributed to the extremely active media coverage regarding COVID-19 in Palestine, where the official government spokesman and the Minister of Health held two press conferences each day on national TV channels concerning the latest updates about COVID-19 in Palestine, as well as relatable information regarding this disease, such as modes of transmission and preventive instructions during the outbreak. These results are in line with the findings of former studies, which revealed that mass media is the major source of information about COVID-19 and SARS epidemics (Lau et al. 2003; Motta Zanin et al. 2020) . However, other previous studies reported that the majority of participants referred to social media in order to obtain information concerning COVID-19, which is relatively inconsistent with our finding (Giao et al. 2020; Bhagavathula et al. 2020b; Abdelhafiz et al. 2020; Saqlain et al. 2020; Aker and Mıdık 2020) . Moreover, 69.6% of our students reported scientific resources as their source of information, which is due to their easy access to highly recommended medical articles and journals available in the university's library. Notwithstanding that official media and scientific resources respectively were seen to be the main sources of information in 83.6% and 81.5% of students with a good knowledge level, 57.5% and 40.7% of these students also considered media and social media as a source of information. On the other hand, 75.9% and 70.7% students with poor knowledge level relied on official media and media respectively as a source of information; furthermore, 61.3% and 51% of these students used scientific resources and social media. The difference in information sources contributed to the variety of knowledge levels. Moreover, besides the presented correct and accurate information, unconfirmed information intended to misinform people can also be rapidly disseminated via the media and social media. With regards to practices, positive and cautious practices with regard to the COVID-19 epidemic were carried out by the vast majority of participants, where 76.8% of the respondents adhered to at least eight practices out of ten, while only 23.2% displayed implementation of at least three negative practices. Our findings revealed that more than 90% of students avoided crowded places, practiced the appropriate methods of coughing and sneezing, washed their hands with soap and water, did not travel between governorates and reduced their presence in public places during the rapid rise period of the COVID-19 outbreak. Furthermore, a high percentage of the students (79.1%) maintained a safe distance between them and other people. This is attributed to the good knowledge level about the mode of transmission and the belief that personal hygiene is optimal for prevention from the disease, in addition to strict prevention and control measures implemented by the Palestinian government. We found our results encouraging, since good hygiene practices, behavioral commitment, and social distancing aid in decreasing the transmission rate of COVID-19. These results are comparable with a study performed in China, where the vast majority of the participants held an optimistic attitude with regard to the COVID-19 epidemic (Zhong et al. 2020) , and with other studies, where the participants revealed generally adequate positive practices with regard to the COVID-19 disease (Truong et al. 2019; Khan et al. 2020; Al Nsour et al. 2020) . Throughout the COVID-19 outbreak, results have shown that two-thirds of participants didn't wear face masks when out in public, while a fifth did not maintain physical distancing. Compliance with the pandemic restrictions is essential and crucial in this phase, and failure to adhere to preventive measures -even if by a minority -would only lead to uncontrolled spreading of the disease. Positive practices with regard to the COVID-19 pandemic were found to be significantly associated with the gender and major of the precipitant. Females were found to have fewer negative practices when compared to males; mainly by avoiding crowded places, practicing coughing and sneezing etiquette, maintaining proper hand hygiene, and avoiding traveling between governorates during the rapid rise of the disease. These findings are in line with other studies which reported association between gender and some positive practices toward COVID-19 (Truong et al. 2019; Zhong et al. 2020; Khader et al. 2020) . Results have also shown that health-care professions students were more compliant with COVID-19 restrictions than students of other faculties. This is comparable to previous studies which investigated KAP towards COVID-19 among participants from a medical and non-medical study group (Truong et al. 2019; Hussain et al. 2020) . Regarding the attitudes towards COVID-19, the majority of participants were found to be worried that a family member would get COVID-19, and believed that the prevention measures should be applied by the whole population. This is in line with multiple previous studies in Egypt (Abdelhafiz et al. 2020) and Pakistan (Mirza et al. 2020) . Although many studies have reported that a significant percentage of the infected people were young (Chen et al. 2020; Bialek et al. 2020; Escalera-Antezana et al. 2020) , our study has shown that less than half of the participants, who are considered young, thought that they can be infected with COVID-19, and nearly one-third thought they were invincible to the disease. Based on the results of the study, a molding of knowledge about COVID-19 into a positive attitude was clearly observed. Interesting differences were noted when comparing students with GKL and AKL, where GKL students tended to be less worried that a family member might get COVID-19, and believed that preventative measures should not be practiced solely by older adults and high risk groups, as compared with AKL students. Furthermore, findings showed that participants with GKL were less likely to find themselves invincible to COVID-19 when compared to those with AKL. Concerning the performance of the local authorities, two-thirds of participants considered the authorities' attempts successful in controlling the spread of COVID-19, and around half of them thought that the preventative measures were sufficient. Furthermore, less than a quarter of the participants believed that local authorities have sufficient tools to deal with the confirmed and suspected cases of COVID-19. These findings disagree with other studies among different communities (Zhong et al. 2020; Rugarabamu et al. 2020; Azlan et al. 2020) ; this might be due to the lack of economic and medical resources and the shortage within the health system compared to developed countries. Our results revealed that students had variable knowledge regarding COVID-19, and the majority depended on the official media briefs in Palestine as a source of information, thus reflecting the need of collaborative efforts between the Ministry of Health and the media to implement more effective tools that increase the knowledge level about COVID-19 and the preventive measures needing to be followed among the community, especially that the protective measures were more adhered by health profession students, which may reveal that an increase in community knowledge would increase their commitment to the preventive measures. With regard to practices, positive and cautious practices with regard to the COVID-19 papidemic were carried out by the vast majority of participants. Positive practices with regard to the COVID-19 pandemic were found to be significantly associated with gender, where females were found to have fewer negative practices when compared to males. Furthermore, the majority of respondents were worried that a family member might get infected with the virus, and considered the preventative measures taken by the Palestinian government at the beginning were sufficient and implemented in a timely manner. The study has potential limitations to be noted. Above all, the participants of the study were students, and this sample of participants is unlikely to be representative of the general Palestinian population. Also, the study participants volunteered to participate in the study (self-selection bias), thus limiting the generalizability of the study findings. Moreover, the collected data was self-reported and depended on the participants' integrity and recall ability, and thus might be subject to recall bias. Taking all the above-mentioned limitations into consideration, more studies should be conducted in the future to evaluate the knowledge, practices, and attitudes toward COVID-19 among different groups of society. 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Table 7 Effect of different significant variables on positive practices of respondents obtained by binary logistic regression (odds ratios and 95% confidence intervals) More PP: n (%) Authors' contributions All authors contributed to the study conception and design. Material preparation and supervision were performed by Hani A. Naseef. Data analysis were performed by Hani A. Naseef and Ni'meh A. Al-Shami. All authors contributed in writing the first draft of the manuscript and commented on previous versions of the manuscript. All authors read and approved the final manuscript. The data used to support the findings of this study are available from the corresponding author upon request.Code availability Not applicable. Ethics approval The study was approved by the IRB committee at Faculty of Pharmacy, Nursing and Health Professions, Birzeit University with reference number BZU-PNH-2006.Consent to participate • We confirm the confidentiality of each participant's answer, and the data will be treated with complete confidentiality, and only for research and statistical purposes only.• We confirm that their participation in the study is voluntary, with no financial compensation. • We confirm the participants' right to not answer any question they do not want to, and their right to withdraw from the study at any time they wish without giving reasons without no negative consequences being applied to them. • Written consent was obtained from each participant before their participation in the study. The corresponding author confirms that the manuscript has been read and approved for submission by all the named authors. The authors state that they do not present any conflict of interests in the present research.