key: cord-0696700-4xgglmjw authors: de Roquetaillade, C.; Chousterman, B.G.; Mebazaa, A. title: Making things right! Shouldn't we screen patients with thromboembolic events for SARS-CoV-2 infection, during the pandemia? date: 2021-03-29 journal: Int J Cardiol DOI: 10.1016/j.ijcard.2021.03.058 sha: ba4901117565c03483439a57e472c52037b819a4 doc_id: 696700 cord_uid: 4xgglmjw nan In the present study of Miro et al. 7 assessed the prevalence of thromboembolic events as a primary manifestation of Covid-19 symptomatology. Their study, which comprises a remarkable sample size of 63 822 COVID patients presenting in emergency department (ED), confirms the association between SARS-CoV-2 infection and thromboembolic events in patients presenting at the ED. In their report, the observed increase in pulmonary embolism (PE) is unequivocal. In addition, observed mild increment in stroke might also suggest a role of the virus on such event. Interestingly, the observed increment in PE was not associated with increased prevalence of deep vein thrombosis. We see This process called immunothrombosis, is supported by several autopsy findings as well as comparative study of radiological patterns between conventional PE and COVID-19 related PE 8 . However, since the population studied was presenting in ED and not necessarily hospitalized, one can hypothesize a less intense pulmonary inflammation. The possibility for immunothrombosis to undergo in mildly affected patients with no respiratory failure deserves further explorations. If proven so, utilisation of anticoagulation therapy among patients with mild symptoms and discharged back home might become loudable 1 . Several studies are actually ongoing, the expected results should bring answers on this specific topic 9 . Antithrombotic therapy in patients with COVID-19? -Rationale and Evidence High Prevalence of Deep Vein Thrombosis in Mechanically Ventilated COVID-19 Patients Unusual arterial thrombotic events in Covid-19 patients Timing and Causes of Death in Severe COVID-19 Patients. Epub ahead of print 5 Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study Excess out-of-hospital deaths during the COVID-19 outbreak: evidence of pulmonary embolism as a main determinant Frequency of five cardiovascular/hemostatic entities as primary manifestations of SARS-CoV-2 infection: Results of the UMC-19-S2. International Journal of Cardiology. Epub ahead of print 30 Clinical and computed tomography characteristics of COVID-19 associated acute pulmonary embolism: A different phenotype of thrombotic disease? COVID-19 and arterial thrombosis: A potentially fatal combination